Functional near-infrared spectroscopy study in children with developmental delay

QUAN Yan; LUO Li; CHEN Ling; WEI Wen-xi; CHEN Ying-rui; LIU Ping; ZHANG Yu; LI Hong-hui; ZENG Ting

doi:10.11852/zgetbjzz2021-0208

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Chinese Journal of Child Health Care ›› 2021, Vol. 29 ›› Issue (7) : 772-774. DOI: 10.11852/zgetbjzz2021-0208

Clinical Research

Functional near-infrared spectroscopy study in children with developmental delay

QUAN Yan^*, LUO Li, CHEN Ling, WEI Wen-xi, CHEN Ying-rui, LIU Ping, ZHANG Yu, LI Hong-hui, ZENG Ting

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Abstract

Objective To study the characteristics of children with developmental delay (DD) by using functional near infrared spectroscopy (fNIRS), so as to provide reference for the individual diagnosis and treatment of DD. Methods A total of 13 children with DD(DD group) and 19 normal children (NC group) were selected in this study, whose brain function was tested by 8-channel fNIRS. Multiscale entropy (MSE) of each channel and the mean MSE of the frontal region between DD group and NC group were compared by t test. Results The mean MSE of DD group (1.570±0.491) was significantly lower than that of NC group (2.075±0.791) (t=2.228, P＝0.034). The MSE values in channel 3 and 8 were significantly different between DD group and NC group(t=2.513, 2.868, P＜0.01). Conclusions Compared with the normal control group, the complexity of frontal lobe spontaneous brain signals in children with DD is significantly lower, indicating that children with DD have bilateral prefrontal brain function impairment.

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functional near-infrared spectroscopy / developmental delay / children

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QUAN Yan, LUO Li, CHEN Ling, WEI Wen-xi, CHEN Ying-rui, LIU Ping, ZHANG Yu, LI Hong-hui, ZENG Ting. Functional near-infrared spectroscopy study in children with developmental delay[J]. Chinese Journal of Child Health Care. 2021, 29(7): 772-774 https://doi.org/10.11852/zgetbjzz2021-0208

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