Research progress on the relationship between microRNA and neuropsychiatric disorders in children

ZHANG Hong-mei; JIA Mei-xiang; LI Su-shui; XUE Man; SUN Zhi-gang

doi:10.11852/zgetbjzz2021-0078

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Chinese Journal of Child Health Care ›› 2022, Vol. 30 ›› Issue (3) : 276-280. DOI: 10.11852/zgetbjzz2021-0078

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Research progress on the relationship between microRNA and neuropsychiatric disorders in children

ZHANG Hong-mei^*, JIA Mei-xiang, LI Su-shui, XUE Man, SUN Zhi-gang

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Abstract

MicroRNA is a group of short endogenous non-coding RNA molecules that regulate gene expression and play an important role in the proliferation, differentiation, synaptic formation, synaptic plasticity and apoptosis of neurons in the central nervous system.A large number of studies have confirmed that changes in the expression pattern of microRNA in different brain regions may be involved in the occurrence and development of children's neuropsychiatric disorders such as autism spectrum disorders.MicroRNA is expected to become a biomarker for early diagnosis and a target for the development of new drugs.

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microRNA / child neuropsychiatric disorder / biomarker / neurodevelopmental disorder

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ZHANG Hong-mei, JIA Mei-xiang, LI Su-shui, XUE Man, SUN Zhi-gang. Research progress on the relationship between microRNA and neuropsychiatric disorders in children[J]. Chinese Journal of Child Health Care. 2022, 30(3): 276-280 https://doi.org/10.11852/zgetbjzz2021-0078

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