Objective To investigate the correlation between video electroencephalogram (VEEG) and Gesell Developmental Scale (GDS) in neonates with convulsion, in order to provide theoretical reference for predicting the prognosis of neonates with convulsion. Methods From July 2015 to August 2019, newborns who were hospitalized with neonatal convulsion and underwent VEEG examination in Yulin Second Hospital were collected as study subjects.VEEG characteristics in the neonatal period was analyzed, GDS test was performed 3 months after birth. Results 1) A total of 43 eligible newborns were included, including 20 cases of mild VEEG abnormality, 10 cases of moderate abnormality and 13 cases of severe abnormality.2) Mild VEEG abnormalities were mainly paroxysmal abnormalities (50%), and the moderate abnormality was mainly paroxysmal abnormality (40.0%) and mature abnormality (30%).Background activity (61.5%) was the main abnormal condition.3) A total of 38 children were followed up, including 6 lost in follow-up.The results of GDS test showed that the prognosis of 15 patients was poor(DQ＜85), with the poor prognosis rate of 40.5%(15/37).4) The prognosis rate of mild, moderate and severe VEEG patients was about 11.1%, 60.0% and 77.8%, respectively.The consistency test of Kappa between the degree of VEEG abnormality and GDS was 0.60.The sensitivity and specificity of predicting the degree of VEEG abnormality were 86.7%, 72.7%, positive predictive value of 68.4% and negative predictive value of 88.9%. Conclusions The predictive value of VEEG and GDS test in neonatal convulsions is not completely consistent.VEEG has high sensitivity and negative predictive value in predicting prognosis, but low specificity and positive predictive value.Clinically, it often takes a long time for comprehensive evaluation to make a more accurate judgment on the neurodevelopment of children with seizures.