Analysis of serum specific IgE in children with allergic rhinitis in Dalian

JIANG Tao, LI Rui, HUA Na, LI Xian-hua

Chinese Journal of Child Health Care ›› 2021, Vol. 29 ›› Issue (8) : 918-921.

PDF(490 KB)
PDF(490 KB)
Chinese Journal of Child Health Care ›› 2021, Vol. 29 ›› Issue (8) : 918-921. DOI: 10.11852/zgetbjzz2020-1724
Experience Exchange

Analysis of serum specific IgE in children with allergic rhinitis in Dalian

  • JIANG Tao, LI Rui, HUA Na, LI Xian-hua
Author information +
History +

Abstract

Objective To explore the distribution and characteristics of serum specific IgE of children with allergic rhinitis(AR) in Dalian,so as to provide reference for clinical diagnosis,treatment and epidemiological prevention of AR. Methods The serum specific IgE results of 312 patients with allergic rhinitis aged less than 14 years from August 2014 to July 2020 were analyzed. The distribution of allergens was compared in different groups by gender,number of allergenic positive cases,number of types of allergenic positive and detection time. Results The top three allergens included house dust mite/duster mite (34.1%),mugwormwood (18.6%) and cat (8.9%),while mutton (0.3%),peanut (0.6%) and crab (0.9%) ranked in the last three places. There were 126 patients positive to single allergen and 186 patients positive to double or more allergens(χ2=15.75,P=0.031). Double (47.8%),triple (26.3%) and quadruple (14.0%) were the most common allergens. Pearson correlation test showed that there was a negative correlation between the original number of allergens and the corresponding number of people (r =-0.800,P= 0.017). There was only 1 case with a maximum of 11 allergens positive. Among the patients with the highest proportion of dual allergens,house dust mite/duster mite + mugwort combination was the most,followed by house dust mite/duster mite + cat combination. The top three allergenic species with the most positive cases in both sexes were house dust mite/duster mite,mugwort and cats. The number of male patients positive to some allergens was higher than that in females,including mugworm,house dust mite/dust mite,house dust,dogs,hops,beef and shrimp(χ2=13.64,11.67,9.45,8.63,10.31,8.36,5.37,P<0.05). Egg white allergen was positive in females more than that in females(χ2=18.67,P=0.027). The number of allergic patients was highest in September (31.41%),August (20.51%) and July (8.01%),when it was the late summer and early autumn in local area,accounting for 59.93% of the total number of patients in the whole year. The month with the lowest number of allergic patients was January (1.60%),March (1.60%) and February (1.88%),when it was the end of winter and the beginning of spring locally,accounting for only 5.08% of the annual number of patients. Conclusion As the common allergens of allergic rhinitis in children in Dalian area,mites,mugwormwood and cats allergens are more prevalent in late summer and early autumn,which should be the focus of local prevention and control.

Key words

allergic rhinitis / allergen / specific IgE / children

Cite this article

Download Citations
JIANG Tao, LI Rui, HUA Na, LI Xian-hua. Analysis of serum specific IgE in children with allergic rhinitis in Dalian[J]. Chinese Journal of Child Health Care. 2021, 29(8): 918-921 https://doi.org/10.11852/zgetbjzz2020-1724

References

[1] Zhang Y,Zhang L. Prevalence of allergic rhinitis in china[J].Allergy Asthma Immunol Res,2014,6(2):105-113.
[2] Kong WJ,Chen JJ,Zheng ZY,et al.Prevalence of allergic rhinitis in 3-6-year-old children in Wuhan of China[J].Clin Exp Allergy,2009,39(6):869-874.
[3] 中华耳鼻咽喉头颈外科杂志编辑委员会鼻科组,中华医学会耳鼻咽喉头颈外科学分会鼻科学组.变应性鼻炎诊断和治疗指南(2015年,天津)[J].中华耳鼻咽喉头颈外科杂志,2016,51(1):6-24.
[4] 王秀萍,隋洪起,吴萍,等.大连市2010年气候特征及影响评估[J].安徽农业科学,2011,39(22):13621-13626.
[5] 杨慧珺,马行凯,陆建斌,等.儿童变应性鼻炎变应原谱及致敏因素分析[J].临床耳鼻咽喉头颈外科杂志,2018,32(21):1636-1640.
[6] 段梦夕,张晓宇,朱鸿,等.大连地区490例0~14岁过敏性疾病儿童常见过敏原检测结果分析[J].基层医学论坛,2017,21(17):2168-2170.
[7] 万丽平,王衍晶,徐萍,等.大连地区儿童过敏原检测结果分析[J].中国当代医药,2015,22(24):123-125.
[8] 王虹茵,曹志伟.辽宁地区0~12岁变应性疾病患儿血清变应原谱分析[J].临床耳鼻咽喉头颈外科杂志,2018,32(20):1546-1550,1556.
[9] 彭晓林,张金梅,王丽生,等.变应性鼻炎患者3292例变应原谱变化分析[J].中华耳鼻咽喉头颈外科杂志,2013,48(6):504-506.
[10] Seidman MD,Gurgel RK,Lin SY,et al.Clinical practice guideline:Allergic rhinitis[J].Otolaryngol Head Neck Surg,2015,152(Suppl 1):1-43.
[11] Brozek JL,Bousquet J,Baena-Cagnani CE,et al.Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines:2010 revision[J].J Allergy Clin Immunol,2010,126(3):466-476.
[12] Wlasiuk G,Vercelli D. The farm effect,or:when,what and how a farming environment protects from asthma and allergic disease[J].Curr Opin Allergy Clin Immunol,2012,12(5):461-466.
PDF(490 KB)

Accesses

Citation

Detail

Sections
Recommended

/