Research progress on the undernutrition and growth hormone/insulin-like growth factor-1 with children

ZHANG Tian; SUN Hai-ling; ZHANG Mei; BAN Bo; SUN Bing

doi:10.11852/zgetbjzz2020-1118

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Chinese Journal of Child Health Care ›› 2021, Vol. 29 ›› Issue (7) : 734-737. DOI: 10.11852/zgetbjzz2020-1118

Review

Research progress on the undernutrition and growth hormone/insulin-like growth factor-1 with children

ZHANG Tian^*, SUN Hai-ling, ZHANG Mei, BAN Bo, SUN Bing

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Abstract

At present, undernutrition is still common among children and adolescents in our country, especially in remote and rural areas of the western China. Children in remote areas often suffer from inadequate intake of protein and trace elements such as zinc and iron due to economic reasons, resulting in growth retardation, low weight and anemia. The growth hormone (GH)/insulin-like growth factor-1 (IGF-1) axis is the main regulator of growth and development in children and adolescents. This review summarizes the effects of undernutrition on the GH/IGF-1 axis and discusses the importance of nutritional status of children in assessing the GH/IGF-1 axis.

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undernutrition / growth hormone / insulin-like growth factor-1

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ZHANG Tian, SUN Hai-ling, ZHANG Mei, BAN Bo, SUN Bing. Research progress on the undernutrition and growth hormone/insulin-like growth factor-1 with children[J]. Chinese Journal of Child Health Care. 2021, 29(7): 734-737 https://doi.org/10.11852/zgetbjzz2020-1118

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