Research progress on the relationship between attention-deficit/hyperactivity disorder and gut microbiota

WANG Ya-ping; DENG Lan-liu; LIU Rui-zhuo; CHEN Li

doi:10.11852/zgetbjzz2020-0802

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Chinese Journal of Child Health Care ›› 2021, Vol. 29 ›› Issue (8) : 865-868. DOI: 10.11852/zgetbjzz2020-0802

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Research progress on the relationship between attention-deficit/hyperactivity disorder and gut microbiota

WANG Ya-ping, DENG Lan-liu, LIU Rui-zhuo, CHEN Li

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Abstract

Attention-deficit/hyperactivity disorder (ADHD) is one of the most common neurodevelopmental disorders in children, which is characterized by inattention, hyperactivity and impulsivity that are not consistent with the developmental level, accompanied by functional impairment in social and academic performance.At present, the etiology of ADHD is not yet clear.It is generally believed that ADHD is a kind of behavioral disease caused by genetics, environment and their interaction, which may be related to dysfunction of the fronto-striatal brain and monoamine neurotransmitter system.Different gut microbiota can produce different neurotransmitters, participating in the regulation of the central nervous system through bidirectional communication of microbiota-gut-brain axis.Therefore, it will open up a new way for early intervention and treatment of ADHD.

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attention-deficit/hyperactivity disorder / gut microbiota / microbiota-gut-brain axis / gut microbial diversity

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WANG Ya-ping, DENG Lan-liu, LIU Rui-zhuo, CHEN Li. Research progress on the relationship between attention-deficit/hyperactivity disorder and gut microbiota[J]. Chinese Journal of Child Health Care. 2021, 29(8): 865-868 https://doi.org/10.11852/zgetbjzz2020-0802

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