Status and influential factors of vitamin A among children aged 0-6 years in the Tibetan Plateau of Ganzi Prefecture, Sichuan Province

HUANG Ping; LIN Xin-mei; GUO Du-ping; BA Xue-guo; WEI Zheng-rong; DING Hong-yan; HE Mao-yun; WANG Quan-sheng; XU Shi-ying; KE Gang

doi:10.11852/zgetbjzz2020-0676

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Chinese Journal of Child Health Care ›› 2021, Vol. 29 ›› Issue (2) : 143-146. DOI: 10.11852/zgetbjzz2020-0676

Status and influential factors of vitamin A among children aged 0-6 years in the Tibetan Plateau of Ganzi Prefecture, Sichuan Province

HUANG Ping^*, LIN Xin-mei, GUO Du-ping, BA Xue-guo, WEI Zheng-rong, DING Hong-yan, HE Mao-yun, WANG Quan-sheng, XU Shi-ying, KE Gang

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Abstract

Objective To investigate the serum vitamin A (VitA) level of 0- to 6-year-old children in Ganzi Tibetan Autonomous Prefecture, so as to provide reference for the prevention of vitamin A related diseases. Methods Totally 2 122 Tibetan children were examined in Xiangcheng and Daocheng counties of Ganzi Prefecture from April 2017 to April 2019, and the content of serum VitA was detected by High Performance Liquid Chromatography. Results The average level of serum VitA in 2 122 children aged 0~6 years was (1.05±0.27)μmol/L.The subclinical deficiency rate was 8.15%, and the suspect subclinical deficiency rate was 45.99%.The average level of VitA in infant group was (0.94±0.26)μmol/L, significantly lower than that in toddlerhood group [(1.09±0.28)μmol/L] and preschool group [(1.05±0.27)μmol/L](F=15.308,P＜0.001).The average VitA level above 4 km was (0.96±0.19)μmol/L, significantly lower than that of 2-3 km [(0.99±0.26)μmol/L] and 3-4 km [(1.12±0.27)μmol/L](F=61.735,P＜0.001).The average level of VitA in summer was higher than that in other seasons(F=52.194,P＜0.001).In addition, the subclinical deficiency rate of 0-1 year old group was 23.97%,significantly higher than that of other age groups(χ² =43.503,P＜0.001).Logistic regression analysis showed that altitude, season and age all had an influence on subclinical deficiency and suspicious subclinical deficiency, and the incidence of subclinical deficiency and suspected subclinical deficiency increased with altitude. Conclusions The average level of VitA in children aged 0-6 years in Ganzi Tibetan Autonomous Prefecture is low, mainly with suspicious subclinical deficiency.The deficiency of VitA is related to age, altitude and season.Children at different ages are suggested to take VitA supplementation and food rich in VitA according to local altitude and season to prevent VitA deficiency and related diseases.

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children aged 0-6 years / vitamin A / suspected subclinical deficiency of vitamin A / subclinical deficiency of vitamin A / altitude / season

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HUANG Ping, LIN Xin-mei, GUO Du-ping, BA Xue-guo, WEI Zheng-rong, DING Hong-yan, HE Mao-yun, WANG Quan-sheng, XU Shi-ying, KE Gang. Status and influential factors of vitamin A among children aged 0-6 years in the Tibetan Plateau of Ganzi Prefecture, Sichuan Province[J]. Chinese Journal of Child Health Care. 2021, 29(2): 143-146 https://doi.org/10.11852/zgetbjzz2020-0676

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