Research progress on hypothermia in the treatment of neonatal hypoxic-ischemic encephalopathy

TIAN Zhi-chen; ZHANG Xuan; YIN Xiao-juan

doi:10.11852/zgetbjzz2020-0360

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Chinese Journal of Child Health Care ›› 2021, Vol. 29 ›› Issue (3) : 292-295. DOI: 10.11852/zgetbjzz2020-0360

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Research progress on hypothermia in the treatment of neonatal hypoxic-ischemic encephalopathy

TIAN Zhi-chen^*, ZHANG Xuan, YIN Xiao-juan

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Abstract

Hypoxic-ischemic encephalopathy (HIE) is the main cause of neonatal death and disability.Mild hypothermia treatment can significantly reduce the mortality and disability rate of HIE.However, there are still some newborns with lifelong disability in movement, sensation and cognition.Therefore, the implementation conditions of mild hypothermia treatment need to be optimized.This article reviews the pathophysiology of HIE, the neuroprotective effect of hypothermia treatment on HIE, and the influence of various parameters of hypothermia treatment on the neuroprotective effect, so as to provide the basis for better clinical application of hypothermia treatment on HIE.

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newborn / hypoxic-ischemic encephalopathy / hypothermia

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TIAN Zhi-chen, ZHANG Xuan, YIN Xiao-juan. Research progress on hypothermia in the treatment of neonatal hypoxic-ischemic encephalopathy[J]. Chinese Journal of Child Health Care. 2021, 29(3): 292-295 https://doi.org/10.11852/zgetbjzz2020-0360

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