Survey and intervention study of sleep in children with postural tachycardia syndrome

GU Ying; WANG Jia-qi; JIA Wan-ru; WU Min; JIAO Fu-yong; SHEN Jie; LIN Jing

doi:10.11852/zgetbjzz2020-0296

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Chinese Journal of Child Health Care ›› 2020, Vol. 28 ›› Issue (4) : 374-378. DOI: 10.11852/zgetbjzz2020-0296

Survey and intervention study of sleep in children with postural tachycardia syndrome

GU Ying^1*, WANG Jia-qi^2*, JIA Wan-ru², WU Min², JIAO Fu-yong³, SHEN Jie⁴, LIN Jing²

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Abstract

Objective To explore the effects of sleep improvement intervention on the clinical symptoms of children with postural tachycardia syndrome (POTS) by investigating the sleep status.Methods Totally 40 children diagnosed with POTS from May 2018 to May 2019 were selected as the POTS group, and meanwhile 20 healthy children for physical examination in child healthcare department were selected as the control group.The diagnosis of POTS were based on the results of head-up tilt test (HUTT).The Pittsburgh Sleep Quality Index (PSQI) was used to investigate sleep status.POTS group received sleep improvement intervention for 3 months.A decrease of orthostatic intolerance score> 2 indicated that the sleep intervention was effective, and ≤2 indicated ineffective.Results Significant differences were found in supine heart rate (t=-2.117), upright maximum heart rate (t=3.88) and upright heart rate difference (t=-7.86) between POTS group and control group(P＜0.05).Compared with the control group, 77.5% of children in POTS group had a total PSQI score of > 5.Except from sleep drugs, significant differences were found in PSQI score (t=8.31,P＜0.001) and six factors of PSQI (P＜0.001) .There was no statistical difference on blood pressure before and after sleep improvement intervention in POTS group.While supine heart rate (t=-2.707), upright maximum heart rate (t=2.656), upright heart rate difference (t=4.771) and clinical symptoms score(Z=-5.083) dramatically decreased after intervention (P＜0.05).Furthermore, 60% of POTS children had a decrease of symptom score > 2.The ROC curve showed that the sleep improvement intervention for POTS would be predicted to be effective when the patients more than 10 years old, yielded a sensitivity of 91.7% and specificity of 43.7%. Conclusions Most children with POTS suffered from poor sleep quality, and sleep intervention therapy can effectively improve the clinical symptoms of POTS children.

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postural tachycardia syndrome / sleep intervention / children and adolescents

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GU Ying, WANG Jia-qi, JIA Wan-ru, WU Min, JIAO Fu-yong, SHEN Jie, LIN Jing. Survey and intervention study of sleep in children with postural tachycardia syndrome[J]. Chinese Journal of Child Health Care. 2020, 28(4): 374-378 https://doi.org/10.11852/zgetbjzz2020-0296

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