Risk factors and prognosis of mycoplasma pneumoniae pneumonia associated with inflammatory tracheostenosis in children

SHENG Jiang-yin; RUAN Gui-ying; YIN Yan-dan; HONG Yan; SU Qun-yan; NAN Xiang-zhen

doi:10.11852/zgetbjzz2020-0287

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Chinese Journal of Child Health Care ›› 2020, Vol. 28 ›› Issue (12) : 1385-1388. DOI: 10.11852/zgetbjzz2020-0287

Risk factors and prognosis of mycoplasma pneumoniae pneumonia associated with inflammatory tracheostenosis in children

SHENG Jiang-yin¹, RUAN Gui-ying^1,2, YIN Yan-dan¹, HONG Yan¹, SU Qun-yan¹, NAN Xiang-zhen²

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Abstract

Objective To investigate risk factors and prognosis of mycoplasma pneumoniae pneumonia (MPP) associated with inflammatory tracheostenosis in children,so as to provide reference of prevention and treatment in children′s MPP. Methods Clinical data of 116 children diagnosed with MPP and treated with bronchoscopy from January 2018 to January 2020 in Yuying Children′s Hospital Affiliated to Wenzhou Medial University were analyzed.According to the results of bronchoscopy,children were divided into the inflammatory tracheostenosis group (n=53) and the normal group (n=63).Clinical manifestations,laboratory and radiological results,and treatment outcome were compared between the two groups.Multiple Logistic regression analysis was used to analyze risk factors of MPP associated with inflammatory tracheostenosis in children. Results Compared with normal group,the levels of CRP(Z=3.368) and LDH(t=4.102),lobar pneumonia(χ²=20.496),fever duration(Z=2.151),cough duration day(χ²=2.527),hospitalization time(t=2.432),hospitalization expenses(Z=2.733) were significantly higher in the inflammatory tracheostenosis group(P＜0.05).LDH≥411 U/L(OR=8.922,95%CI:2.982-26.695),CRP≥22.9 mg/L(OR=4.857,95%CI:1.530-15.414)and lobar pneumonia(OR=4.857,95%CI:1.530-15.414)were risk factors for MPP in children with inflammatory tracheostenosis. Conclusions CRP≥22.9 mg/L,LDH≥411 U/L and lobar pneumonia can be the risk factors for MPP in children with inflammatory tracheostenosis.MPP Children associated with inflammatory tracheostenosis have poor clinical outcome and should be early treated by bronchoscopy.

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mycoplasma pneumoniae pneumonia / inflammatory tracheostenosis / risk factors / prognosis

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SHENG Jiang-yin, RUAN Gui-ying, YIN Yan-dan, HONG Yan, SU Qun-yan, NAN Xiang-zhen. Risk factors and prognosis of mycoplasma pneumoniae pneumonia associated with inflammatory tracheostenosis in children[J]. Chinese Journal of Child Health Care. 2020, 28(12): 1385-1388 https://doi.org/10.11852/zgetbjzz2020-0287

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