Research progress on the preventive application of glutamine in necrotizing enterocolitis in premature infants

ZHANG Hai-jian; ZHU Ming-zhe

doi:10.11852/zgetbjzz2020-0213

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Chinese Journal of Child Health Care ›› 2021, Vol. 29 ›› Issue (3) : 285-288. DOI: 10.11852/zgetbjzz2020-0213

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Research progress on the preventive application of glutamine in necrotizing enterocolitis in premature infants

ZHANG Hai-jian, ZHU Ming-zhe

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Abstract

Necrotizing enterocolitis (NEC) is one of the most common acute and fatal gastrointestinal emergencies in premature infants,mainly manifested as abdominal distension,hematochetia,etc.In severe cases,intestinal perforation and even septicemia may occur.The etiology and pathogenesis is unclear,some studies have found that intestinal mucosa barrier damage may be related to its pathogenesis,glutamine (Gln),the essential amino acid for human body,plays an irreplaceable role in maintaining intestinal mucosal integrity and reducing intestinal mucosal damage and ischemic necrosis.This paper reviews the preventive application of glutamine in NEC in premature infants.

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glutamine / necrotizing enterocolitis / premature infants

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ZHANG Hai-jian, ZHU Ming-zhe. Research progress on the preventive application of glutamine in necrotizing enterocolitis in premature infants[J]. Chinese Journal of Child Health Care. 2021, 29(3): 285-288 https://doi.org/10.11852/zgetbjzz2020-0213

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