Effect of different intensive feeding methods on the physical growth of very preterm and extremely preterm infants after discharge

DONG Ping; FU Shi-yun; TANG Xin-rui; LYU Yu-jing; YAN Dong-yong; XU Xiu

doi:10.11852/zgetbjzz2019-1896

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Chinese Journal of Child Health Care ›› 2020, Vol. 28 ›› Issue (10) : 1088-1092. DOI: 10.11852/zgetbjzz2019-1896

Effect of different intensive feeding methods on the physical growth of very preterm and extremely preterm infants after discharge

DONG Ping, FU Shi-yun, TANG Xin-rui, LYU Yu-jing, YAN Dong-yong, XU Xiu

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Abstract

Objective To investigate the effects of different intensive feeding methods on catch-up growth of very preterm and extremely preterm infants (VPT/EPT) and body composition (BC) development,in order to provide theoretical support for the post-discharge healthcare of VPT/EPT. Methods Totally 91 VPT and EPTs followed up in the outpatient clinic of Children′s Hospital of Fudan University were enrolled in this study from April 2018 to October 2019,and were given individualized intensive feeding guidance.Physical examination and BC assessment were performed monthly after corrected gestational age of 40 weeks. Results Compared with partial breastfeeding and formula feeding groups,the breastfeeding group had a lower weight-for-age Z score at 4,5 and 6 months(P=0.042,0.033,0.037),a lower weight-for-length Z score at the age of 6 months (P=0.016).In terms of BC,the body fat percentage at the age of 4 months was significantly lower than that of partial breastfeeding and formula feeding groups (25% vs.28.1% vs.28.8%,P=0.015).And the fat-free mass index (FFMI) at the age of 6 months in the breastfeeding group was significantly higher than that in the formula feeding group (13.08 vs.11.78,P=0.034). Conclusions Breastfed VPT/EPT in early life may tend to have an impaired weight gain and body fat deposit.Further studies with larger cohorts and research on the long-term consequences of these early differences are warranted.

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very preterm / extremely preterm / growth / body composition / intensive feeding after discharge

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DONG Ping, FU Shi-yun, TANG Xin-rui, LYU Yu-jing, YAN Dong-yong, XU Xiu. Effect of different intensive feeding methods on the physical growth of very preterm and extremely preterm infants after discharge[J]. Chinese Journal of Child Health Care. 2020, 28(10): 1088-1092 https://doi.org/10.11852/zgetbjzz2019-1896

References

[1] Blencowe H,Cousens S,Chou D,et al.Born too soon:the global epidemiology of 15 million preterm births[J].Reprod Health,2013,10(Suppl 1):2.
[2] Pampanini V,Boiani A,De Marchis C,et al.Preterm infants with severe extrauterine growth retardation (EUGR) are at high risk of growth impairment during childhood[J].Eur J Pediatr,2015,174(1):33-41.
[3] Chan E,Quigley MA.School performance at age 7 years in late preterm and early term birth:a cohort study[J].Arch Dis Child Fetal Neonatal Ed,2014,99 (6):F451-F457.
[4] Van Dommelen P,Van der Pal SM,Bennebroek Gravenhorst J,et al.The effect of early catch-up growth on health and well-being in young adults[J].Ann Nutr Metab,2014,65 (2-3):220-226.
[5] Sicard M,Nusinovici S,Hanf M,et al.Fetal and postnatal head circumference growth:synergetic factors for neurodevelopmental outcome at 2 years of age for preterm infants[J].Neonatology,2017,112 (2):122-129.
[6] 《中华儿科杂志》编辑委员会,中华医学会儿科学分会儿童保健学组,中华医学会儿科学分会新生儿学组.早产、低出生体重儿出院后喂养建议[J].中华儿科杂志,2016,54(1):6-12.
[7] Zachariassen G,Faerk J,Grytter C,et al.Nutrient enrichment of mother′s milk and growth of very preterm infants after hospital discharge[J].Pediatrics,2011,127(4):e995-e1003.
[8] Voortman T,Leermakers ET,Franco OH,et al.A priori and a posteriori dietary patterns at the age of 1 year and body composition at the age of 6 years:the Generation R Study[J].Eur J Epidemiol,2016,31(8):775-783.
[9] Colaizy TT,Carlson S,Saftlas AF,et al.Growth in VLBW infants fed predominantly fortified maternal and donor human milk diets:a retrospective cohort study[J].BMC Pediatr,2012,12:124.
[10] Schanler RJ,Shulman RJ,Lau C.Feeding strategies for premature infants:beneficial outcomes of feeding fortified human milk versus preterm formula[J].Pediatrics,1999,103(6 Pt 1):1150-1157.
[11] O′Connor DL,Jacobs J,Hall R,etal.Growth and development of premature infants fed predominantly human milk,predominantly premature infant formula,or a combination of human milk and premature formula[J].J Pediatr Gastroenterol Nutr,2003,37(4):437-446.
[12] Amissah EA,Brown J,HardingJE.Protein supplementation of human milk for promoting growth in preterm infants[J].Cochrane Database Syst Rev,2018,6:CD000433.
[13] Koo W,Tice H.Human milk fortifiers do not meet the current recommendation for nutrients in very low birth weight infants[J].JPEN J Parenter Enteral Nutr,2018,42(4):813-820.
[14] Cooke RJ.Postnatal growth and development in the preterm and small for gestational age infant[J].Nestle Nutr Workshop Ser Pediatr Program,2010,65:85-95.
[15] 全美盈,王长燕,王丹华.50例超低出生体重儿追赶生长的临床研究[J].中国儿童保健杂志,2015,23(11):1149-1152.
[16] 章晓婷,龚华,陈文,等.极低出生体重儿出院后营养与生长发育监测[J].中华临床营养杂志,2016,24(5):299-302.
[17] Goldstein RF,Malcolm WF.Care of the neonatal intensive care unit graduate after discharge[J].Pediatr Clin North Am,2019,66(2):489-508.
[18] 童梅玲,张敏,池霞,等.84例早产适于胎龄儿第一年体格追赶生长纵向评估[J].中国当代儿科杂志,2011,13 (1) :12-15.
[19] Dotinga BM,Eshuis MS,Bocca-Tjeertes IF,et al.Longitudinal growth and neuropsychological functioning at age 7 in moderate and late preterms[J].Pediatrics,2016,138 (4):e20153638.