Serum 25-hydroxy vitamin D status and the influencing factors in 351 healthy preschool children

WANG Xi-rui; YU Xiao-dan; ZHANG Li-shan; XU Lei; YUAN Yi-chun

doi:10.11852/zgetbjzz2019-1882

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Chinese Journal of Child Health Care ›› 2020, Vol. 28 ›› Issue (10) : 1101-1105. DOI: 10.11852/zgetbjzz2019-1882

Serum 25-hydroxy vitamin D status and the influencing factors in 351 healthy preschool children

WANG Xi-rui¹, YU Xiao-dan¹, ZHANG Li-shan², XU Lei², YUAN Yi-chun³

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Abstract

Objective To investigate the levels of serum vitamin D and its influencing factors in preschool children in Shanghai,so as to provide theoretical basis for the prevention and treatment of vitamin D deficiency in this area. Methods A total of 351 preschool children (185 boys and 166 girls) aged 3 to 6 years from 3 kindergartens in Pudong New Area,Shanghai,were randomly selected in this study.Serum 25-hydroxyvitamin D[25-(OH)D]levels were measured by liquid chromatography-tandem mass spectrometry (LC-MS/MS) and the data of relevant influencing factors was obtained by standardized questionnaire. Results The average level of 25-(OH)D in preschool children was (28.1±6.7)ng/ml.Vitamin D deficiency (≤20 ng/ml) was observed in 35 children (10.0%),and 316(90.0%) children had optimal vitamin D level (20～100 ng/ml).Multivariate analysis showed that the low frequency of vitamin D supplementation and the older age (≥6 years old) were the risk factors of 25-(OH)D deficiency in preschool children (P＜0.05). Conclusions Age and vitamin D supplementation have significant effect on Vitamin D levels of preschool children.The vitamin D supplement rate is relatively low in the older group (≥6 years old).Considering current vitamin D deficiency in preschool children,popular science education of children′s health care should be strengthened to increase the vitamin D supplementation rate in combination with the actual individual situation,as well as to increase outdoor activity time,thereby promoting the health of preschool children.

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preschool children / 25-hydroxyvitamin D / vitamin D deficiency

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WANG Xi-rui, YU Xiao-dan, ZHANG Li-shan, XU Lei, YUAN Yi-chun. Serum 25-hydroxy vitamin D status and the influencing factors in 351 healthy preschool children[J]. Chinese Journal of Child Health Care. 2020, 28(10): 1101-1105 https://doi.org/10.11852/zgetbjzz2019-1882

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