Objective To study on the relationships between serum vitamin A and E levels and thymus (T) cellular immunity in children with recurrent respiratory infection,in order to provide basis for clinical treatment. Methods A total of 60 children with recurrent respiratory infection admitted in Lu'an People's Hospital from March 2016 to August 2019 were enrolled in study group,and 53 healthy children were selected as control group.Serum vitamin A,vitamin E and T cellular immunological indicators of the two groups were detected and compared.Pearson correlation analysis was used to explore the relationship between serum vitamin A,E levels and T cellular immunity of children in the study group. Results The levels of vitamin A,cluster of differentiation (CD) CD3+,CD4+ and CD4+/CD8+ in the study group were significantly lower than those in control group,while the CD8+ in study group was significantly higher than that in control group (P<0.05).The vitamin E levels in the two groups were similar (P＞0.05).In the study group,the level of vitamin A was positively correlated with CD3+,CD4+ and CD4+/CD8+levels(r=0.769,0.814,0.795, P<0.05),and negatively correlated with the CD8+levels(r=-0.752,P<0.05).However,vitamin E level was not significantly related to the indexes of T cellular immunology(P＞0.05). Conclusion s There is a close correlation between serum vitamin A and T cell immunity in children with recurrent respiratory tract infection.The higher the serum vitamin A level,the stronger the T cell immunity,but there is no significant correlation between serum vitamin E and T cell immunity.
Key words
recurrent respiratory infection /
vitamin A /
vitamin E /
T cellular immunity
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