Neuroprotective effect of remote ischemic post-conditioning on neonatal hypoxic-ischemic encephalopathy

SONG Lin; GUO Jin; SONG Fu-xiang; ZHANG Peng

doi:10.11852/zgetbjzz2019-1662

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Chinese Journal of Child Health Care ›› 2020, Vol. 28 ›› Issue (11) : 1219-1222. DOI: 10.11852/zgetbjzz2019-1662

Neuroprotective effect of remote ischemic post-conditioning on neonatal hypoxic-ischemic encephalopathy

SONG Lin, GUO Jin, SONG Fu-xiang, ZHANG Peng

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Abstract

Neonatal hypoxic-ischemic encephalopathy (HIE) is one of the main causes of neonatal death and disability from all over the world,mainly due to the decrease or complete block of cerebral blood flow during perinatal period.And most newborn survivors have movement disorder and cognitive impairment.As a new treatment for HIE,remote ischemic post-conditioning (RIPostC) has many advantages,such as easy operation,low cost and safe.In addition,it can reduce the infarct area and brain edema,improve nerve cells and regulate various cell pathways to alleviate the nerve injury of HIE.In this paper,the effect of remote ischemic post-conditioning on the morphological signal transduction pathway and prognosis of nerve cells is briefly discussed.

Key words

hypoxic-ischemic encephalopathy / brain injury / remote ischemic post-conditioning / neonate

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SONG Lin, GUO Jin, SONG Fu-xiang, ZHANG Peng. Neuroprotective effect of remote ischemic post-conditioning on neonatal hypoxic-ischemic encephalopathy[J]. Chinese Journal of Child Health Care. 2020, 28(11): 1219-1222 https://doi.org/10.11852/zgetbjzz2019-1662

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