Objective To explore whether there is abnormal brainstem auditory evoked potential (BAEP) in children with attention deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD),and to analyze the differences. Methods A total of 27 children with ADHD (53 ears) and 26 children with ASD (52 ears) aged 6 to 16 years old were selected as ADHD group and ASD group respectively in Xiamen Xian Yue Hospital from October 2018 to April 2019,meanwhile 50 healthy volunteers (100 ears) were recruited as the control group.BAEP was detected in ADHD group and ASD group by evoked potential instrument.The latency of Ⅰ,Ⅲ,Ⅴ waves,the interval of Ⅰ-Ⅲ,Ⅲ-Ⅴ,Ⅰ-Ⅴ waves and the abnormal amplitude of Ⅰ,Ⅴ waves were analyzed and compared. Results Compared with the control group,the ADHD and ASD groups showed shorter Ⅰ-wave latency,shorter Ⅰ-Ⅴ interval,and higher I and Ⅴ amplitudes.The rate of shorter Ⅰ wave latency in ADHD group and ASD group was 5.66% and 25.00% respectively,and the rate of increasing amplitude of wave Ⅰ was 24.53% and 50.00% respectively,and the differences were statistically significant(χ2=7.601,7.294,P<0.05).Compared with ASD group,the I wave amplitude in the ADHD group significantly reduced,the Ⅴ wave amplitude and the Ⅴ/Ⅰ amplitude ratio significantly increased (Z=-2.491,-2.205,-3.140,P<0.05). Conclusion There are differences on auditory pathways between ADHD and ASD children,and the difference in Ⅴ/Ⅰ amplitude ratio can be used as an important objective indicator for the diagnosis of ADHD and ASD.
Key words
attention deficit hyperactivity disorder /
autism spectrum disorder /
brainstem auditory evoked potential
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