Objective To test the validity and reliability of the Chinese version of Hammersmith Infant Neurological Examination (HINE). Methods Totally 59 children aged 2 months to 1 year old in diagnosis of high-risk infants with cerebral palsy were selected according to Chinese guidelines for rehabilitation of cerebral palsy (2015),devided into two groups by gestational-age,premarure group (32 to 36 weeks gestational-age) and term-infant group (37 to 42 weeks gestational-age).30 normal children matched with group in age were selected.All children were evaluated with the Chinese version of HINE.The total score of HINE and each factor score among the three groups were used to discriminate validity.As the gold standard the diagnosis of high-risk children with cerebral palsy,ROC was used to determine the cutoff point,tensitivity and specificity.10 cases were randomly selected from each group and re-examined and evaluated by the same physician 1 week after the first examination to test the test-retest reliability.10 cases were randomly selected from each group.The two groups of evaluators simultaneously conducted the examination and scoring of the HINE to test the inter-rater reliability. Results The total score of scale and the scores of 5 items in the preterm and term-infant groups were lower than those in the normal control group, and the differences were statistically significant (P＜0.01).The area under the ROC curve of the preterm group was 0.95, when the limit was 21 points,the sensitivity was 0.97,and the specificity was 0.93.While the area under the ROC curve of the term-infant group was 0.93, when the limit was 26 points,the sensitivity was 0.97,and the specificity was 0.95. The sensitivity and specificity of both groups were ≥0.9.For the inter-rater reliability and the test-retest reliability,the intraclass correlation coefficient (ICC) of total score were both >0.80,the intraclass correlation coefficient (ICC) of the scores of 5 items was >0.70 and >0.80 respectively. Conclusions The Chinese version of HINE has good validity and reliability,high sensitivity and specificity.It could be used as a clinical screening instrument for high-risk cerebral palsy children aged from 2 months to 1 year.
Key words
high-risk cerebral palsy children /
the Chinese version of Hammersmith Infant Neurological Examination /
reliability /
validity
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