Research advances on the genomic biomarkers of autism spectrum disorder

WEI Nian-jin; WANG Yu

doi:10.11852/zgetbjzz2019-0762

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Chinese Journal of Child Health Care ›› 2020, Vol. 28 ›› Issue (5) : 551-554. DOI: 10.11852/zgetbjzz2019-0762

Research advances on the genomic biomarkers of autism spectrum disorder

WEI Nian-jin, WANG Yu

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Abstract

Autism spectrum disorder (ASD) is a neurodevelopmental disease characterized by impairment social interaction,repetitive behaviors and restricted interest. Recent studies have demonstrated dramatically increasing prevalence of ASD,reaching to 1∶59. However,the etiology and pathogenesis of ASD remain unknown. Early diagnosis and early intervention are crucial to the rehabilitation of ASD. In recent years,researches on biological markers of ASD has made great progress,especially in genomics,including gene mutation,copy number variation,single nucleotide polymorphism and epigenetic. This review will summarize the research progress on genomic biomarkers of ASD.

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autism spectrum disorders / biomarker / copy number variant / epigenetic

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WEI Nian-jin, WANG Yu. Research advances on the genomic biomarkers of autism spectrum disorder[J]. Chinese Journal of Child Health Care. 2020, 28(5): 551-554 https://doi.org/10.11852/zgetbjzz2019-0762

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