Objective To analyze the application value of general movements(GMs) combined with Dubowitz neurological examination in the evaluation of neurodevelopment in asphyxiated premature infants. Methods A total of 60 premature asphyxiated infants treated in the neonatal ward of the Affiliated Hospital of Nantong University from February 2017 to March 2018 were enrolled in the study,and were divided into brain injury group(n=28) and non-brain injury group(n=32)according to the consensus of experts on brain injury of premature infants in 2012. Dubowitz neurological examination was performed at least twice within 7 days after birth and 40 weeks after correcting gestational age. GMs screening and re-screening were performed in the pre-term stage,writhing movements stage and fidgety movements stage.Children′s Developmental Center of China(CDCC) was conducted at the corrected age of 3,6 and 12 months old.The early diagnostic value of GMs combined with Dubowitz neurological examination in brain injury of premature infants with asphyxia and its correlation with CDCC were analyzed. Results 1)The sensitivity and specificity of GMs combined with Dubowitz neurological examination in predicting brain injury in premature infants with asphyxia were 96.43% and 84.38%,respectively. 2)The positive rate of GMs combined with Dubowitz in screening for brain injury in premature infants was positively correlated with the CDCC(PDI、MDI) score at 3,6 and 12 months of gestational age (r=0.71,0.66;0.67,0.59;0.73,0.71),and the correlation was the strongest at 12 months. Conclusion GMs combined with Dubowitz neurological examination can be used as an effective means for early diagnosis of brain injury in premature infants with asphyxia.
Key words
general movements /
Dubowitz neurological examination /
asphyxia /
premature infants /
brain injury
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