Objective To investigate the correlation between bisphenol A(BPA) exposure and metabolic syndrome in school-age girls. Methods From September 2016 to September 2017,314 primary school students were randomly selectedfrom Chongchuan District,Gangzha District and Tongzhou Districtto collect urine samples and conduct BPA concentration testing.According to the results of BPA detection,the participants were divided into BPA exposure group and BPA non-exposure group.At the same time,the physical condition of the two groups of children,including body mass index(BMI),systolic blood pressure(SBP),diastolic blood pressure(DBP),fasting blood glucose(FBG),fasting insulin(FIS),triglyceride(TG),total cholesterol(TC) and high-density lipoprotein cholesterol(HDL-C),were measured and evaluated.The differences of each indicator between the two groups and the relationship between each metabolic index and BPA exposure were analyzed. Results Among school-age girls,there were 232 girls in the BPA exposure group and 82 girls in the BPA non-exposure group.The detection rate of BPA was 73.89%.The BMI,SBP,FBG,FIS,TG,and TC of the BPA exposure group were higher than those of the BPA non-expoure group(P<0.05).The HDL-C of the BPA exposwre group was lower than that of the BPA non-exposure group(P<0.05).There were 58 girls (49 girls in the BPA exposure group,9 girls in the non-exposure group) who were overweight and obese,and the detection rate of overweight and obesity was 18.47%.The incidence of overweight and obese girls in the BPA exposure and non-exposure groups wassignificantly different(χ2 = 4.14,P<0.05).Eight girls met the criteria for metabolic syndrome,all in the BPA exposure group. Conclusion Bisphenol A exposure is prevalent in school-age girls.Girls exposed to BPA are more likely to be overweight and obese.In children with metabolic syndrome,the indicators were higher in BPA-exposed girls than in BPA-non-exposed girls,suggesting that there is a correlation between BPA exposure and metabolic syndrome in school-age girls,and exposure to BPA may be one of the risk factors for metabolic syndrome.
Key words
bisphenol A /
metabolic syndrome /
school-age girls
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