Research progress on motor development in infants with prenatal iron deficiency

LI Ming-yan; ZHAO Zheng-yan

doi:10.11852/zgetbjzz2019-0158

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Chinese Journal of Child Health Care ›› 2019, Vol. 27 ›› Issue (11) : 1192-1195. DOI: 10.11852/zgetbjzz2019-0158

Research progress on motor development in infants with prenatal iron deficiency

LI Ming-yan, ZHAO Zheng-yan

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Abstract

Iron deficiency (ID) and iron deficiency anemia (IDA) are the most common nutrient deficiency worldwide.Pregnant women and infants are the high-risk population of ID.Maternal ID,to a certain extent,may affect fetal/neonatal iron status.ID in early life affects motor development of individual mainly through alteration of myelination,striatal and dopamine neurotransmitter system.Early postnatal iron supplementation can correct ID in circulation and tissue,but can not completely reverse the behavioral changes caused by ID during pregnancy.Therefore,it is of great significance to further study the effect of prenatal ID and its reversibility on motor development in infancy,and to clarify the critical time window of iron therapy for improving children′s quality of life and long-term prognosis.

Key words

irondeficiency / myelination / dopamineneurotransmitter / motordevelopment / infants

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LI Ming-yan, ZHAO Zheng-yan. Research progress on motor development in infants with prenatal iron deficiency[J]. Chinese Journal of Child Health Care. 2019, 27(11): 1192-1195 https://doi.org/10.11852/zgetbjzz2019-0158

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