Research advances on intestinal microbes and childhood autism spectrum disorders

BAI Mao-fei; WANG Xia

doi:10.11852/zgetbjzz2019-0134

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Chinese Journal of Child Health Care ›› 2019, Vol. 27 ›› Issue (9) : 986-989. DOI: 10.11852/zgetbjzz2019-0134

Research advances on intestinal microbes and childhood autism spectrum disorders

BAI Mao-fei, WANG Xia

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Abstract

Autism spectrum disorders(ASD)is a serious neurodevelopmental disorder,and its core symptoms include the lack of social function,social communication barriers,limitations of interest and stereotyped behavior,caused by the interaction of genetic and environmental factors. Intestinal microorganisms are a large number of microorganisms present in the intestine,which not only affect the ability to digest and absorb,but also affect the brain development and function through the gut-brain axis. Specific probiotics can regulate the balance of human micro-ecology,maintain normal metabolic absorption and immune defense functions. Intestinal microbial disorders in critical stages of infant development may increase the risk of ASD,and affect the development of ASD in children through neuroendocrine,immune,and metabolite pathways. Therefore,probiotics treatment is promising to be a new adjuvant treatment for ASD.

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intestinal microorganisms / autism spectrum disorder / children

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BAI Mao-fei, WANG Xia. Research advances on intestinal microbes and childhood autism spectrum disorders[J]. Chinese Journal of Child Health Care. 2019, 27(9): 986-989 https://doi.org/10.11852/zgetbjzz2019-0134

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