Correlations among lactose intolerance,calcium intake and bone health

WU Hai-lin, ZHAN Xue

Chinese Journal of Child Health Care ›› 2019, Vol. 27 ›› Issue (11) : 1201-1203.

PDF(442 KB)
PDF(442 KB)
Chinese Journal of Child Health Care ›› 2019, Vol. 27 ›› Issue (11) : 1201-1203. DOI: 10.11852/zgetbjzz2019-0099

Correlations among lactose intolerance,calcium intake and bone health

  • WU Hai-lin, ZHAN Xue
Author information +
History +

Abstract

Lactose intolerance is considered to be concerned with calcium intake and bone health.It is generally believed that lactose intolerance can reduce calcium intake,but its effect on calcium absorption rate is still controversial.Lactose appears to be an important factor of calcium absorption among lactose intolerant populations,and different doses of lactose in earlier study designs may also be responsible for different results.In recent decades,lactase related gene types have been found to be an important factor affecting calcium intake and bone health.However,being limited by knowledge and technology,the heterogeneity among previous studies is large,which contributes to the contradictory data aggregation in related studies.So more reliable and larger samples of control studies are warranted in order to explore the correlation among lactose intolerance,calcium intake and bone health.

Key words

lactoseintolerance / lactosemalabsorption / calciumintake / calciumabsorption / bonehealth

Cite this article

Download Citations
WU Hai-lin, ZHAN Xue. Correlations among lactose intolerance,calcium intake and bone health[J]. Chinese Journal of Child Health Care. 2019, 27(11): 1201-1203 https://doi.org/10.11852/zgetbjzz2019-0099

References

[1] Suchy FJ,Brannon PM,Carpenter TO,et al.NIH consensus development conference statement:lactose intolerance and health[J].Nih Consens State Sci Statements,2010,27(2):1-27.
[2] Stefano MDI,Veneto G,Malservisi S,et al.Lactose malabsorption and intolerance and peak bone mass[J].Gastroenterology,2002,122(7):1793-1799.
[3] Pawłowska K,Seredyński R,Umławska W,et al.Hydrogen excretion in pediatric lactose malabsorbers:relation to symptoms and the dose of lactose[J].Arch Med Sci,2018,14(1):88-93.
[4] Wilt TJ,Shaukat A,Shamliyan T,et al.Lactose intolerance and health[J].Evid Rep Technol Assess,2010,192(192):1-410.
[5] Laaksonen MM,Mikkila V,Rasanen L,et al.Genetic lactase non-persistence,consumption of milk products and intakes of milk nutrients in finns from childhood to young adulthood[J].Br J Nutr,2009,102(1):8-17.
[6] Zhao J,Fox M,Cong Y,et al.Lactose intolerance in patients with chronic functional diarrhoea:the role of small intestinal bacterial overgrowth[J] .Aliment Pharmacol Ther,2010,31(8):892-900.
[7] Tomba C,Baldassarri A,Coletta M,et al.Is the subjective perception of lactose intolerance influenced by the psychological profile?[J].Aliment Pharmacol Ther,2012,36(7):660-669.
[8] Jellema P,Schellevis FG,Dawm VAD,et al.Lactose malabsorption and intolerance:a systematic review on the diagnostic value of gastrointestinal symptoms and self-reported milk intolerance[J].QJM,2010,103(8):555-572.
[9] Tolonen S,Laaksonen M,Mikkila V,et al.Lactase gene c/t(-13910) polymorphism,calcium intake,and pQCT bone traits in finnish adults[J].Calcif Tissue Int,2011,88(2):153-161.
[10] Treister-Goltzman Y,Friger R,Peleg M.Does primary lactase deficiency reduce bone mineral density in postmenopausal women? A systematic review and meta-analysis[J].Osteoporosis Int,2018,1-9:2399-2407.
[11] Winzenberg TM,Shaw K,Fryer J,et al.Calcium supplementation for improving bone mineral density in children[J].Cochrane Database Syst Rev,2006,2:CD005119.
[12] Händel MN,Heitmann BL,Abrahamsen B.Nutrient and food intakes in early life and risk of childhood fractures:a systematic review and meta-analysis[J].Am J Clin Nutr,2015,102(5):1182-1195.
[13] Goulding A,Rockell JE,Black RE,et al.Children who avoid drinking cow′s milk are at increased risk for prepubertal bone fractures[J].J Am Diet Assoc,2004,104(2):250-253.
[14] Manias K,McCabe D,Bishop N.Fractures and recurrent fractures in children; varying effects of environmental factors as well as bone size and mass[J].Bone,2006,39(3):652-657.
[15] Pires LA,Souza AC,Laitano O,et al.Bone mineral density,milk intake and physical activity in boys who suffered forearm fractures[J].J Pediatr (Rio J),2005,81(4):332-336.
[16] Larson NI,Neumark-Sztainer D,Harnack L,et al.Calcium and dairy intake:Longitudinal trends during the transition to young adulthood and correlates of calcium intake[J].J Nutr Educ Behav,2009,41(4):254-260.
[17] BaldanA,Tagliati S,Saccomandi D,et al.Assessment of lactose-free diet on the phalangeal bone mineral status in italian adolescents affected by adult-type hypolactasia[J].Nutrients,2018,10(5):E558.
[18] Kwak HS,Lee WJ,Lee MR.Revisiting lactose as an enhancer of calcium absorption[J].Int Dairy J,2012,22(2):147-151.
[19] Obermayer-Pietsch BM,Gugatschka M,Reitter S,et al.Adult-type hypolactasia and calcium availability:decreased calcium intake or impaired calcium absorption?[J].Osteoporos Int,2007,18(4):445-451.
[20] Tremaine WJ,Newcomer AD,Riggs BL,et al.Calcium absorption from milk in lactase-deficient and lactase-sufficient adults[J].Dig Dis Sci,1986,31(4):376-378.
[21] Vandenplas Y.Lactose intolerance[J].Asia Pac J Clin Nutr,2015,24(Suppl):9-13.
[22] Griessen M,Cochet B,Infante F,et al.Calcium absorption from milk in lactase-deficient subjects[J].Am J Clin Nutr,1989,49(2):377.
[23] Saulnier DMA,Spinler JK,Gibson GR,et al.Mechanisms of probiosis and prebiosis:considerations for enhanced functional foods[J].Curr Opin Biotechnol,2009,20(2):135-141.
[24] Bronner F.Recent developments in intestinal calcium absorption[J].Nutr Rev,2010,67(2):109-113.
[25] Cochet B,Jung A,Griessen M,et al.Effects of lactose on intestinal calcium absorption in normal and lactase-deficient subjects[J].Gastroenterology,1983,84(5):935.
[26] Dawsonhughes B.Interaction of dietary calcium and protein in bone health in humans[J]. J Nutr,2003,133(Suppl 3):852-854.
[27] Bikle DD,Tahimic C,Chang W,et al.Role of IGF-I signaling in muscle bone interactions[J].Bone,2015,80:79-88.
PDF(442 KB)

Accesses

Citation

Detail

Sections
Recommended

/