Research progress on probiotics in preventing necrotizing enterocolitis in premature infants

FENG Meng-ni; KE Hua; LI Zhan-kui; ZHANG Li

doi:10.11852/zgetbjzz2019-0070

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Chinese Journal of Child Health Care ›› 2019, Vol. 27 ›› Issue (6) : 629-632. DOI: 10.11852/zgetbjzz2019-0070

Research progress on probiotics in preventing necrotizing enterocolitis in premature infants

FENG Meng-ni¹, KE Hua², LI Zhan-kui², ZHANG Li²

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Abstract

Necrotizing enterocolitis (NEC) is an extremely serious acquired gastrointestinal disease in the neonatal period,especially in premature infants.Because of its high morbidity,mortality and high risk of poor prognosis,NEC has been receiving much attention for many years,but its pathogenesis has not been fully understood.In recent years,there have been many studies pointing out that intestinal micro-ecological disorders are closely related to the occurrence of the disease.And probiotic,as a biological agent regulating intestinal micro-ecology,has gradually attracted the attention of researchers.This review summarizes the characteristics of neonatal intestinal flora and the research hotspots of probiotics in preventing NEC in premature infants.

Key words

probiotic / intestinal flora / premature / necrotizing enterocolitis

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FENG Meng-ni, KE Hua, LI Zhan-kui, ZHANG Li. Research progress on probiotics in preventing necrotizing enterocolitis in premature infants[J]. Chinese Journal of Child Health Care. 2019, 27(6): 629-632 https://doi.org/10.11852/zgetbjzz2019-0070

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