Objective To assess the cognitive function and characteristics of children with epilepsy by using Wechsler Intelligence Scale for Children,Fourth Edition (WISC-Ⅳ),and to analyze the influencing factors of cognitive function in epilepsy children . Method Totally 45 children with epilepsy were screened according to the International League Against Epilepsy (ILAE) criteria from August 2016 to October 2017,and 36 matched healthy children were selected as control group.Cognitive function assessment was performed on all children with WISC-Ⅳ.Also,the characteristics and effects of cognitive function in epilepsy children were analyzed. Results The WISC-Ⅳ test showed that epilepsy group scored significantly lower in the total IQ,four indexes,and subtests than control group,and showed poorer performance in terms of cognitive efficiency(t=6.008,P<0.05).Parental education,medication time,frequency of seizures,and education forms could affect the cognitive efficiency of epilepsy children.Moreover,fathers′ education was a high-risk factor. Conclusions The application of WISC-Ⅳ can intuitively identify the advantages and disadvantages of cognitive function in epilepsy children,thereby providing evidence for early cognitive intervention.
Key words
epilepsy children /
Wechsler Intelligence Scale for children,Fourth Edition /
cognitive efficiency /
cognitive assessment
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References
[1] Manor L,Streiner DL,Yam WKL,et al.Age-related variables in childhood epilepsy:how do they relate to each other and to quality of life?[J].Epilepsy & Behavior,2013,26(1):71-74.
[2] Koo YS,Yang KS,Seok HY,et al.Characteristics of patients with epilepsy who use a website providing healthcare information about epilepsy in South Korea[J].Epilepsy & Behavior,2012,25(2):156-161.
[3] Guzeva OV,Guzeva VI,Guzeva VV,et al.The Results of an evaluation of quality of care and life in children with epilepsy[J].Pediatrician (St Petersburg),2017,8(2):32-43
[4] Kellermann TS,Bonilha L,Lin JJ,et al.Mapping the landscape of cognitive development in children with epilepsy[J].Cortex,2015,66:1-8.
[5] Eun-Hee Kim,Tae-Sung Ko.Cognitive impairment in childhood onset epilepsy:up-to-date information about its causes [J].Korean J Pediatr,2016,59(4):155-164.
[6] Seidenberg M,Pulsipher DT,Hermann B.Cognitive progression in epilepsy[J].Neuropsychol Rev,2007,17(4):445-454.
[7] 李毓秋.韦氏儿童智力量表第四版的结构变化及其对儿童认知能力的评估[J].教育测量与评价,2009,2(4):4-7.
[8] Berg AT,Berkovic SF,Brodie MJ,et al.Revised terminology and concepts for organization of seizures and epilepsies:Report of the ILAE Commission on Classification and Terminology,2005-2009[J].Epilepsia,2010,51(4):676-685.
[9] 丁怡,杨凌燕,郭奕龙,等.《韦氏儿童智力量表-第四版》性能分析[J].中国特殊教育,2006,13(9):37-44.
[10] Gottlieb L,Zelko,Kim FAD,et al.Cognitive proficiency in paediatric epilepsy[J].Epilepsy Behavior,2012,23(2):146-151.
[11] Atugonza R,Kakooza-Mwesige A,Lhatoo S,et al.Multiple anti-epileptic drug use in children with epilepsy in Mulago hospital,Uganda:a cross sectional study[J].BMC Pediatrics,2016,16(1):1-10.
[12] Thompson PJ,Duncan JS.Cognitive decline in severe intractable epilepsy[J].Epilepsia,2005,46(11):1780-1787.
[13] Navab E.Parents of children with epilepsy captured by epilepsy:a qualitative study[J].Acta Medica Mediterranea,2016,32(4):1302-1309.
[14] Kolar SMM,Govindappa L,Sinha S.Outcome of a school-based health education program for epilepsy awareness among school children[J].Epilepsy & Behavior,2016,57:77-81.
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