Objective To investigate the characteristic of intelligence and response inhibition function in children with attention deficit hyperactivity disorder (ADHD) or comorbid ADHD and oppositional defiant disorder (ODD),in order to provide reference for ODD aggravating cognitive function of ADHD . Method Children diagnosed with comorbid ADHD and ODD (ADHD+ODD),simple ADHD (ADHD) and normal controls participated in this study from January 2015 to November 2017,with 30 children in each group.All three groups were matched by age and gender.The diagnosis were made according to Diagnostic and Statistical Manual of Mental Disorders-Fifth Edition (DSM-5) criteria.The Wechsler Intelligence Scale for Children-fourth edition (WISC-Ⅳ) and Stroop text were administered to assess the intelligence and response inhibition functions. Results The scores of VCI,WMI,PSI,CPI,full scale intelligence quotient (FSIQ) and word interference in two case groups were much lower than those in normal controls(F=3.663,5.761,5.436,9.468,6.412,all P<0.05);The general ability index in ADHD+ODD group was lower than that of normal controls(F=2.751,P<0.05),the scores of time for word interference in two case groups were much longer than those in normal controls(F=7.910,P<0.05).However,there were no significant difference on both intelligence and response inhibition function between the two case groups(F=2.703,0.578,both P>0.05). Conclusions Children with ADHD have intelligence and response inhibition function deficit no matter comorbidity or non-comorbidity of oppositional defiant disorder.Comorbid ADHD and ODD have additional influence on the general ability,but not on response inhibition function characteristics of children with ADHD.
Key words
attention deficit hyperactivity disorder /
oppositional defiant disorder /
intelligence /
response inhibition /
comorbidity
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