Research advances on soluble transferrin receptor for diagnosing iron deficiency in children

YANG Ying; GAO Zhen-yan; YAN Chong-huai

doi:10.11852/zgetbjzz2018-26-09-11

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Chinese Journal of Child Health Care ›› 2018, Vol. 26 ›› Issue (9) : 969-972. DOI: 10.11852/zgetbjzz2018-26-09-11

Research advances on soluble transferrin receptor for diagnosing iron deficiency in children

YANG Ying^1,2, GAO Zhen-yan², YAN Chong-huai²

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Abstract

Iron deficiency (ID) continues to be a public health concern worldwide. Among children in the developing world, ID is the most common single-nutrient deficiency, with potentially severe consequences on child neurodevelopment and behavior. Therefore, pediatricians and other healthcare providers should strive to eliminate iron deficiency, the early diagnosis and treatment of the ID are of great value. Soluble transferrin receptor (sTfR) is sensitive to the inadequate delivery of iron to bone marrow and tissue, and is not affected by inflammation. Compared with other methods for screening for ID, sTfR has unique advantage. This review summarizes the use of sTfR for the diagnosis of ID in children, in order to provide reference for early diagnosis of ID in children.

Key words

iron deficiency / soluble transferrin receptor / ROC curve / children

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YANG Ying, GAO Zhen-yan, YAN Chong-huai. Research advances on soluble transferrin receptor for diagnosing iron deficiency in children[J]. Chinese Journal of Child Health Care. 2018, 26(9): 969-972 https://doi.org/10.11852/zgetbjzz2018-26-09-11

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