Pesearch progress on the effect of prebiotics on intestinal mucosal immunity and allergic diseases

YAO Wei-ming; XING Meng-juan; HU Yan

doi:10.11852/zgetbjzz2018-26-08-12

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Chinese Journal of Child Health Care ›› 2018, Vol. 26 ›› Issue (8) : 854-857. DOI: 10.11852/zgetbjzz2018-26-08-12

Pesearch progress on the effect of prebiotics on intestinal mucosal immunity and allergic diseases

YAO Wei-ming, XING Meng-juan, HU Yan

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Abstract

Early preventive strategies of allergic diseases are beneficial to block the allergy march and to improve the quality of life. Most studies have shown that prebiotics, similar to human milk oligosacharides, might involve into intestinal mucosal immunity regulation by impacting intestinal flora species or quantity, producing short chain fatty acids and so on, thereby triggering allergic diseases. Although there is no consistent conclusion about the effect of prebiotics on immunity regulation and allergy prevention, more and more evidence show that prebiotics intervention seems to be one of the most important strategies to prevent allergic diseases.

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prebiotics / mucosal immunity / allergic diseases / infants

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YAO Wei-ming, XING Meng-juan, HU Yan. Pesearch progress on the effect of prebiotics on intestinal mucosal immunity and allergic diseases[J]. Chinese Journal of Child Health Care. 2018, 26(8): 854-857 https://doi.org/10.11852/zgetbjzz2018-26-08-12

References

[1] di Mauro G, Bernardini R, Barberi S, et al. Prevention of food and airway allergy: consensus of the Italian Society of Preventive and Social Paediatrics, the Italian Society of Paediatric Allergy and Immunology, and Italian Society of Pediatrics[J]. World Allergy Organ J, 2016, 9(1): 28.
[2] Fiocchi A, Pawankar R, Cuello-Garcia C, et al.World allergy organization-McMaster University guidelines for allergic disease prevention(GLAD-P):probiotics[J]. World Allergy Organ J, 2015, 8(1):4.
[3] 王艳艳, 彭咏梅. 人乳低聚糖研究进展[J]. 中国实用儿科杂志, 2009, 24(11): 882-884.
[4] Gourbeyre P, Desbuards N, Grémy G, et al. Perinatal and postweaning exposure to galactooligosaccharides/inulin prebiotics induced biomarkers linked to tolerance mechanism in a mouse model of strong allergic sensitization[J]. J Agric Food Chem, 2013, 61(26): 6311-6320.
[5] Knipping K, Orsi A, Boehm G, et al. Microbial and immune biomarkers in infants at risk for allergies fed an intact cow′s milk formula containing specific non-digestible carbohydrates[J]. J Nutr Disorders Ther, 2012, 2:119.
[6] Sierra C, Bernal MJ,Blasco J, et al. Prebiotic effect during the first year of life in healthy infants fed formula containing GOS as the only prebiotic: a multicentre, randomised, double-blind and placebo-controlled trial[J]. Eur J Nutr, 2015, 54(1):89-99.
[7] van Hoffen E, Ruiter B, Faber J, et al. A specific mixture of short-chain galacto-oligosaccharides and long-chain fructo-oligosaccharides induces a beneficial immunoglobulin profile in infants at high risk for allergy[J]. Allergy, 2009,64(3):484-487.
[8] Vos AP, Knol J, Stahl B, et al. Specific prebiotic oligosaccharides modulate the early phase of a murine vaccination response[J]. Int Immunopharmacol, 2010,10(5): 619-625.
[9] Borovik T, Skvortsova V,Belyaeva I,et al.Immune respinse in preterm infants receiving a preterm formula supplemented with GOS/FOS[J].Early Human Development, 2012,88(S2): S115-S115.
[10] Licht TR, Ebersbach T, Frokiar H. Prebiotics for prevention of gut infections[J].Trends in Food Science & Technology,2012,23(2) :70-82.
[11] Kim MH, Kang SG, Park JH, et al.Short-chain fatty acids activate GPR41 and GPR43 on intestinal epithelial cells to promote inflammatory responses in mice[J]. Gastroenterology, 2013,145(2): 396-406.
[12] Maslowski KM, Vieira AT, Ng A, et al. Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43[J].Nature,2009,461 (7268):e1282- e1286.
[13] Raes M, Scholtens PA, Alliet P, et al .Exploration of basal immune parameters in healthy infants receiving an infant milk formula supplemented with prebiotics[J].Pediatr Allergy Immunol, 2010, 21(2 Pt 2): e377-e385.
[14] Scalabrin DM, Mitmesser SH, Welling GW, et al. New prebiotic blend of polydextrose and galacto-oligosacchar-ides has a bifidogenic effect in young infants[J]. J Pediatr Gastroenterol Nutr, 2012, 54(3):343-352.
[15] Braegger C, Chmielewska A, Decsi T, et al. Supplementation of infant formula with probiotics and/or pre-biotics: a systematic review and comment by the ESPGHAN committee on nutrition[J]. J Pediatr Gastroenterol Nutr, 2011, 52(2):238-250.
[16] Mugambi MN, Musekiwa A, Lombard M,et al.Synbiotics, probiotics or prebiotics in infant formula for full term infants:a systematic review[J]. Nutr J, 2012, 11(1):81.
[17] van Hoffen, Ruiter B, Faber J, et al.A specific mixture of short-chain galacto-oligosaccharides and long-chain fructooligosaccharides induces a beneficial immunoglobulin profile in infants at high risk for allergy[J]. J Allergy, 2009, 64(3): 484-487.
[18] Gruber C, van Stuijvenberg M, Mosca F, et al.Reduced occurrence of early atopic dermatitis because of immunoactive prebiotics among low-atopy-risk infants[J].J Allergy Clin Immunol, 2010, 126(4) :791-797.
[19] OsbornDA , Sinn JK. Prebiotics in infants for prevention of allergy[J]. Cochrane Database Syst Rev,2013,3 (4):CD006475.
[20] Cuello-Garcia CA, Fiocchi A, Pawankar R,et al.World allergy organization-McMaster University guidelines for allergic disease prevention(GLAD-P):prebiotics[J]. World Allergy Organization J, 2016,9:10.
[21] Williams HC, Grindlay DJ .What′s new in atopic eczema? An analysis of systematic reviews published in 2007 and 2008. Part 2. Disease prevention and treatment[J]. Clin Exp Dermatol, 2010, 35(3):223-227.
[22] Hogenkamp A, Thijssen S, van Vlies N, et al. Supplementing pregnant mice with a specific mixture of nondigestible oligosaccharides reduces symptoms of allergic asthma in male offspring[J]. J Nutr, 2015. 145(3): 640-646.
[23] S Arslanoglu S, Moro GE, Boehm G, et al. Early neutral prebiotic oligosaccharide supplementation reduces the incidence of some allergic manifestations in the first 5 years of life[J]. J Biol Regul Homeost Agents,2012,26(3 Suppl): 49-59.
[24] Dang D, Zhou W,Lun ZJ, et al. Meta-analysis of probiotics and/or prebiotics for the prevention of eczema[J]. J Int Med Res, 2013, 4(5):1426-1436.
[25] Braegger C, Chmielewska A, Decsi T, et al. Supplementation of infant formula with probiotics and/or pre-biotics: a systematic review and comment by the ESPGHAN committee on nutrition[J]. J Pediatr Gastroenterol Nutr, 2011, 52(2):238-250.
[26] Chiang WC, Huang CH,Llanora GV, et al .Anaphylaxis to cow′s milk formula containing short-chain galacto-oligosaccharide[J]. J Allergy Clin Immunol, 2012, 130(6):1361-1367.