Roles of qualitative magnetic resonance imaging and general movements assessments for predicting motor development in very preterm infants

PANG Zong-lin; WEI Lin-lin

doi:10.11852/zgetbjzz2018-26-05-17

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Chinese Journal of Child Health Care ›› 2018, Vol. 26 ›› Issue (5) : 525-528. DOI: 10.11852/zgetbjzz2018-26-05-17

Roles of qualitative magnetic resonance imaging and general movements assessments for predicting motor development in very preterm infants

PANG Zong-lin¹, WEI Lin-lin²

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Abstract

Objective To compare the predictive value of qualitative MRI of brain structure and general movements assessments for motor development outcome in very preterm infants. Methods Totally 68 very preterm infants from Neonatal Department and Rehabilitation Department of Women＆Children′s Health Care Hospital of Linyi were enrolled in this study. And MRI was conducted at children′s term-equivalent age in order to evaluate white matter abnormality (WMA).Also, general movements were assessed at corrected age of 1 and 3 months. Motor outcome at corrected age of one year old was evaluated by the Gesell Developmental Schedules and the diagnosis of cerebral palsy made by pediatricians. The associations of MRI and GMs assessments with motor developmental outcome were analyzed, and the sensitivity, specificity, positive predictive value and negative predictive value of MRI and GMs assessment for abnormal motor developmental outcome were calculated. Results MRI and GMs assessments were significantly correlated to motor development outcome. MRI demonstrated the great accuracy in predicting motor outcome with specificity of 98.1% and relatively low sensitivity of 43.8%. On the other hand, GMs assessment had the highest sensitivity and relatively low specificity. Conclusions Neuroimaging (MRI) and functional (GMs) assessments play important complementary roles in predicting motor development of very preterm infants.

Key words

motor development / cerebral palsy / general movements assessment / MRI / very preterm infants

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PANG Zong-lin, WEI Lin-lin. Roles of qualitative magnetic resonance imaging and general movements assessments for predicting motor development in very preterm infants[J]. Chinese Journal of Child Health Care. 2018, 26(5): 525-528 https://doi.org/10.11852/zgetbjzz2018-26-05-17

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