Research progress on the association of phthalates with children attention deficit  hyperactivity disorder

HU Dan; HE Hui-min; SUN Jin; XIAO Xu-wu

doi:10.11852/zgetbjzz2018-26-05-15

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Chinese Journal of Child Health Care ›› 2018, Vol. 26 ›› Issue (5) : 518-520. DOI: 10.11852/zgetbjzz2018-26-05-15

Research progress on the association of phthalates with children attention deficit hyperactivity disorder

HU Dan, HE Hui-min, SUN Jin, XIAO Xu-wu

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Abstract

With the increasing deterioration of environment problems, the impact of environmental toxicants on the development of children′s neuropsychological behavior has become a hot social issue. Attention deficit hyperactivity disorder (ADHD) is one of the most common mental and behavioral disorders in childhood, and environmental toxicants may contribute to child ADHD symptoms and disease. Increasing toxicological and epidemiological evidence suggests that there may be associations between phthalates (PAEs) and children′s ADHD symptoms and disease. The potential mechanisms may involve dopamine neuronal, thyroid system, oxidative stress and testosterone modification abnormalities. It is essential to understand the correlation and potential mechanisms between PAEs and ADHD in children for further etiology and pathogenesis study.

Key words

attention deficit hyperactivity disorder / Phthalates / children

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HU Dan, HE Hui-min, SUN Jin, XIAO Xu-wu. Research progress on the association of phthalates with children attention deficit hyperactivity disorder[J]. Chinese Journal of Child Health Care. 2018, 26(5): 518-520 https://doi.org/10.11852/zgetbjzz2018-26-05-15

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