Objective To compare effects of individualized health management and routine intervention on children with simple obesity for one year,and to explore a more effective intervention model for obese children. Methods A total of 130 simple obese children aged 3~8 were enrolled,and were randomly assigned to an individualized diet,exercise,behavioral intervention (individualized group) and general intervention (routine group).After one-year intervention,body mass index (BMI),waist circumference,body fat percentage,glucose and lipid metabolism and C-creative protein (CRP) were compared between two groups and body shape index of different genders,different places of study were compared before and after intervention among the individualized groups. Results After 1 year of intervention,the decrease of BMI,waist circumference,body weight and body fat percentage in the individual group was more obvious than those in the routine group (P<0.001).The height growth of the individualized group was higher than that of the routine group (P<0.001).The levels of fasting blood glucose,fasting insulin,LDL,TG,TC and CRP in the individual group were lower than those in the routine group (P<0.01),and HDL was higher than that in the routine group (P<0.01). Conclusion Individualized health management can effectively improve the body shape of simple obese children aged 3~8.Improving the levels of glucose,lipid metabolism and CRP is an effective intervention model for obese children.
Key words
individualized health management /
childhood obesity /
simple obesity /
intervention /
treatment
{{custom_sec.title}}
{{custom_sec.title}}
{{custom_sec.content}}
References
[1] WHO.Obesity and overweight[EB/OL].Fact sheet.[2016-6].http://www.who.int/mediacentre/factsheets/fs311/en/.
[2] 全明辉,陈佩杰,何晓龙.上海市3~6岁学龄前儿童超重、肥胖率调查——基于2010年国民体质监测[J].中国运动医学杂志,2014,11(33):1047-1053.
[3] 王向军,杨漾,吴艳强,等.上海市7~18岁学生1985至2014年的超重和肥胖流行趋势[J].中国循征儿科杂志,2017,12(2):126-130.
[4] Chan M.WHO Director-General opens a meeting of the childhood obesity commission[EB/OL].Geneva,Switzerland.[2014-7-17].http://www.who.int/dg/speeches/2014/childhood-obesity/en/.
[5] Waters E,de Silva-Sanigorski A,Hall BJ,et al.Interventions for preventing obesity in children[J].Cochrane Database Syst Rev,2011,12:CD001871.
[6] 张祚建,董燕,毕连枝,等.体检中个体化健康管理模式的应用效果评价[J].实用医药杂志,2016,33(10):913-915.
[7] WHO.Child Growth Standard[2006].http://www.who.int/childgrowth/standards/technical_report/en/.
[8] WHO.Growth reference data for 5~19 years[2007].http://www.who.int/growthref/en/.
[9] R Core Team (2017).A language and environment for statistical computing.Foundation for Statistical Computing,2017[EB/OL].[2017-8-4].https://www.R-projec.org.
[10] Bastien M,Poirier P,Lemieux I,et al.Overview of epidemiology and contribution of obesity to cardiovascular disease[J].Prog Cardiovasc Dis,2014,56(4):369-381.
[11] Kreitschmann-Andermahr I,Suarez P,Jennings R,et al.GH/IGF-I regulation in obesity--mechanisms and practical consequences in children and adults[J].Horm Res Paediatr,2010,73(3):153-160.
[12] 王慧,郭丽丽,梁虹,等.血清生长激素水平与儿童单纯性肥胖伴身高略矮的关系[J].现代生物医学进展,2015,15(7):1304-1305.
[13] 马丽.肥胖儿童的代谢特征和临床干预效果分析[J].中国儿童保健杂志,2017,25(3):297-300.
[14] 曹娟,田彦军,李静,等.儿童青少年血脂水平与血压相关性[J].中国公共卫生,2017,33(3):390-395.
[15] Verrotti A,Penta L,Zenzeri L,et al.Childhood obesity:prevention and strategies of intervention.A systematic review of school-based interventions in primary schools[J].J Endocrinol Invest,2014,37(12):1155-1164.
[16] Lumeng CN,Saltiel AR.Inflammatory links between obesity and metabolic disease[J].J Clin Invest,2011,121(6):2111-2117.
[17] Karalis KP,Giannogonas P,Kodela E,et al.Mechanisms of obesity and related pathology:linking immune responses to metabolic stress[J].FEBS J,2009,276(20):5747-5754.
[18] 陈年发,段永强.内皮素-1和C反应蛋白在单纯性肥胖儿童血管内皮细胞损伤中的作用[J].实用儿科临床杂志,2010,25(7):486-487.
[19] 易彦.单纯性肥胖儿童CRP与心血管疾病风险因子的相关性研究[J].心血管病防治知识:学术版,2016,10(1):87-89.