Objective To investigate the prevalence and prognosis of premature infants in Beijing Obstetrics and Gynecology Hospital,Capital Medical University over the past five years,so as to provide epidemiological data for related research. Methods The data of 6 038 live-born premature infants(gestational age< 37 weeks) born in obstetrics department from January 2013 to December 2017 were collected.And the data were analyzed according to premature labor cause(spontaneous premature and iatrogenic premature) and gestational age of delivery,including very early premature infants with gestational age <28 weeks,early premature infants with gestational age of 28-< 32 weeks,middle premature infants with gestational age of 32-<34 weeks and late premature infants with gestational age of 34-<37 weeks. Results The annual prevalence of premature infants in this hospital was 7.38% to 8.57% from 2013 to 2017,with an average rate of 8.03%.However,the proportion of late premature infants in all preterm infants has been on the rise over the past five years,reaching 74.25% by 2017.The top three causes of iatrogenic preterm birth included gestational hypertension(978,39.96%),placenta previa(478,19.53%) and fetal distress(222,9.07%).The prevalence rate of severe asphyxia in iatrogenic early preterm infants was higher(4.1% vs.1.2%,P<0.05) and birth weight was lower than that in spontaneous early preterm infants[(1 338.0±264.4)g vs.(1 381.8±328.0)g,P<0.05)].Moreover,the birth weight of iatrogenic midterm preterm infants was lower than that of spontaneous midterm preterm infants[(1 843.9±341.5)g vs. (1 897.0±392.7)g, P<0.05)],and the hospitalization rate of iatrogenic late preterm infants was higher than that of spontaneous late preterm infants(43.9% vs.38.8%,P<0.01). Conclusions The proportion of late preterm infants is on the rise.Compared with spontaneous preterm infants in the corresponding gestational weeks,iatrogenic early preterm infants are prone to have higher rate of severe asphyxia,lower birth weight of early and middle preterm infants,and higher rate of hospitalization.So it is supposed to strengthen the management of iatrogenic preterm pregnancy and pay attention to iatrogenic premature infants.
Key words
iatrogenic preterm birth /
spontaneous preterm birth /
prevalence rate /
epidemiology
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