Objective To observe the effect of repetitive transcranial magnetic stimulation (rTMS) combined with rehabilitation training on children with language development disorder.Methods Totally 86 children hospitalized in the rehabilitation center of Henan Children′s Hospital from February 2017 to February 2018 were enrolled in this study,and were randomly divided into observation group and control group,with 43 children in each group.Before and after treatment,comprehension,expression,basic operation ability,communication attitude,development quotient and language development quotient of children in different groups were assessed with the Chinese version of S-S language development retardation evaluation method developed by China Rehabilitation Research Center. Results After treatment,the efficacy in observation group was significantly better than that in control group (95.35% vs.79.07%,χ2=5.108,P<0.05).Moreover,the developmental quotient andlanguage developmental quotient of children in both groups significantly increased after treatment (t=4.827,5.009,P<0.05). Conclusion As a new electrophysiological technique for early intervention of language development disorder,rTMS combined with rehabilitation training has better effect on improving the language development ability.
Key words
repetitive transcranial magnetic stimulation /
language dysplasia /
rehabilitation therapy
{{custom_sec.title}}
{{custom_sec.title}}
{{custom_sec.content}}
References
[1]Gupta M,Rajak BL,Bhatia D,et al.Effect of r-TMS over standard therapy in decreasing muscle tone of spastic cerebral palsy patients[J].J Med Eng Technol,2016,40(4):210-216.
[2]Anderkova L,Rektorova I.Cognitive effects of repetitive transcranial magnetic stimulation in patients with neurodegenerative diseases-clinician′s perspective[J].J Neurol Sci,2014,339(1-2): 15-25.
[3] Hoe M,Nakagami E,Green MF,et al.The causal relationships between neurocognition,social cognition and functional outcome over time in schizophrenia:a latent difference Score approach [J].Psycho Medicine,2012,42(11):2287-2299.
[4] Chen J,Silk T,Seal M,et al.Widespread decreased grey and white matter in paediatric obsessive-compulsive disorder (OCD):a voxel-based morphometric MRI study [J].Psychiatry Res,2013,213(1):11-17.
[5] 徐亚琴,胡小沙,梁沂,等.发育性语言障碍儿童的 Gesell测评分析[J],中国儿童保健杂志,2013,21(1):71-73.
[6] 鲍克秀,杨忠秀,李新剑,等.经颅磁刺激联合语言训练对儿童语言发育迟缓的应用价值[J].现代生物医学进展,2017,17(27):5331-5334.
[7] Shriberg LD,Tomblin JB,McSweeny JL.Prevalence of speech delay in 6-year-old chidren and comorbidity with language impairment[J].J Speech Lang Hear Res,1999,42(6):1461-1481.
[8] McQuiston S,Kloczko N.Speech and language development: monitoring process and problems[J].Pediatr Rev,2011,32(6):230-238.
[9] Rhea P,Courtenay FN.Language disorder from infancy through adolescence:listening,speaking,reading,writing,and communicating[M].4th ed.United States of America:ELSEVIER,2012:68-77.
[10] 王贞,李胜利.不同儿童语言障碍特点及主要相关因素[J].中国康复理论与实践,2013,19(6):536-540.
[11] Nojima K,Iramina K.Relationship between rTMS effects and MEP features before rTMS[J].Neurosci Lett,2018,664:110-115.
[12] Yip CW,Cheong PW,Green A,et al.A prospective pilot study of repetitive transcranial magnetic stimulation for gait dysfunction in vascular parkinsonism[J].Clin Neurol Neurosurg,2013,115( 7) : 887-891.
[13] Emara TH,Moustafa RR,Elnahas NM,et al.Repetitive transcranial magnetic stimulation at 1Hz and 5Hz produces sustained improvement in motor function and disability after ischaemic stroke[J].Eur J Neurol,2010,17(9): 1203-1209.
[14] ZhaoJ,Li Z,Cong Y,et al.Repetitive transcranial magnetic stimulation improves cognitive function of Alzheimer′s disease patients[J].Oncotarget,2017,8(27):33864-33871.
[15] Fox MD,Buckner RL,White MP,et al.Efficacy of transcranial magnetic stimulation targets for depression is related to intrinsic functional connectivity with the subgenual cingulate [J].Biol Psychiatry,2012,72(7): 595-603.
[16]Heiss WD.Imaging effects related to language improvements by rTMS [J].Restor Neurol Neurosci,2016,34(6):531-536.
[17] Zhang H,Chen Y,Hu R,et al.rTMS treatments combined with speech training for a conduction aphasia patient: A case report with MRI study[J].Medicine,2017,96(32):e7399.
[18] Lawrence BJ,Gasson N,Bucks RS,et al.Cognitive training and noninvasive brain stimulation for cognition in parkinson′s disease: a Meta-analysis[J].Neurorehabil Neural Repair,2017,31(7):597-608.
PDF(575 KB)
