Research progress on the correlation between intestinal flora and autism spectrum disorder

KUNG Wei-yen; WANG Yu

doi:10.11852/zgetbjzz2018-1166

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Chinese Journal of Child Health Care ›› 2019, Vol. 27 ›› Issue (4) : 407-410. DOI: 10.11852/zgetbjzz2018-1166

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Research progress on the correlation between intestinal flora and autism spectrum disorder

KUNG Wei-yen, WANG Yu

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Abstract

Autism spectrum disorder (ASD) is a neurodevelopmental disorder mainly characterized by social communication disorders, repetitive behaviors and narrow interests.The etiology of ASD is complex, and it focuses on the genetic and environmental factors.As the pathogenesis is unknown, there is no effective treatment.It is found that gastrointestinal diseases and changes of intestinal flora are common in ASD children.Recent studies have shown a two-way interaction between the gut nervous system and the central nervous system, called the microbiota-gut-brain axis.Gut flora regulates brain function through neuroendocrine, immune and intestinal nervous systems and thus affects brain development and behavior.Therefore, the imbalance of intestinal flora may be related to the occurrence of ASD.This article will summarize the effect of intestinal flora on ASD and the progress of related treatment.

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autism spectrum disorder / intestinal flora / microbiota-gut-brain axis

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KUNG Wei-yen, WANG Yu. Research progress on the correlation between intestinal flora and autism spectrum disorder[J]. Chinese Journal of Child Health Care. 2019, 27(4): 407-410 https://doi.org/10.11852/zgetbjzz2018-1166

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