Objective To evaluate the effect of precise intervention on children's eating problems,in order to provide theoretical reference for clinical dietary management. Methods Totally 70 children aged 1-4 years with dietary behavior problems fromJanuary to June 2016, were enrolled in this study and were randomly divided into intervention group and control group. The intervention group was given precise intervention,such as etiological treatment,nutrition support,eating skill,behavior therapy and so on. The control group received routine feeding instruction and the dietary behavior of the two groups was evaluated in 3 months. The effects of two groups were compared in the aspects of feeding behavior and physical development index of children. Results The differences on children's dietary behavior problem,feeding behavior problem and the change of children's weight were significant between intervention group and control group(P<0.05). However,the significant difference on the height of the two groups was not found(P>0.05). Conclusion Precision intervention can promote the healthy development of children via improving dietary behavior and feeding behavior,which is worth of clinical application.