Metabolomics progress on the influence of gestational diabetes mellitus on children′s lung maturity

XIAO Ping-juan; SHAO Qing-liang

doi:10.11852/zgetbjzz2018-0623

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Chinese Journal of Child Health Care ›› 2019, Vol. 27 ›› Issue (6) : 617-619. DOI: 10.11852/zgetbjzz2018-0623

Metabolomics progress on the influence of gestational diabetes mellitus on children′s lung maturity

XIAO Ping-juan, SHAO Qing-liang

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Abstract

If pregnant women with gestational diabetes mellitus (GDM) maintain hyperglycaemia with bad control,fetal insulin secretion will be stimulated to grow in quantity,thereby causing maternal high insulin hematic disease.When maternal insulin concentration increases,the fetus glucocorticoid secretion will be suppressed,which will finally lead to fetal alveolus development lag and hypoglycemia.At present,fetal lung maturity is judged by amniotic fluid bubble test,and there is a big controversy about line amniotic cavity puncture because it is an invasive operation and has certain disadvantages.With the increasing researches on metabonomics of gestational diabetes,this review will summarize recent progress on the impact of child lung mature from the perspective of metabolomics.

Key words

gestational diabetes mellitus / offspring / lung maturity / metabonomics

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XIAO Ping-juan, SHAO Qing-liang. Metabolomics progress on the influence of gestational diabetes mellitus on children′s lung maturity[J]. Chinese Journal of Child Health Care. 2019, 27(6): 617-619 https://doi.org/10.11852/zgetbjzz2018-0623

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