Objective To analyze the growth status of preterm infants discharged from neonatal intensive care unit(NICU) at the age of 0-24 months,in order to provide evidence for growth monitoring and nutrition management of preterm infants. Methods The data of growth development of preterm infants discharged from NICU in Children's Hospital of Shanghai were retrospectively collected from January 2013 to December 2017. The body length and weight of preterm infants aged 0-24 months in different gender and age groups were analyzed. Results A total of 1 143 cases were included, and the extremely early and early term infants account for the largest proportion of premature group, which was 36.8%.Moderately preterm accounted for 29.6% and late preterm accounted for 33.6%.The average gestational age was(32.2±2.4) weeks, and there was no significant difference in the composition of birth age in gender(χ2=2.048,P=0.562).The average height and weight of preterm infants at adjusted age of 0 month exceeded that of the full-term infants.Preterm infants at adjusted age of 1 month achieved catch-up growth, but the height and body weight of preterm infants were still lower than those of full-term infants.Besides, the catch-up growth of preterm male infants was undesirable. Conclusions Appropriate catch-up growth is the goal of nutrition management for preterm infants after discharge,and the preterm male infants should be paid more attention to. Also,systematic nutrition management will facilitate appropriate catch-up growth.
Key words
neonatal intensive care unit /
preterm infants /
catch-up growth /
systematic management
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References
[1] 世界卫生组织.关于早产的事实[R].[2018-05-06].http://www.who.int/zh/news-room/fact-sheets/detail/preterm-birth.
[2] 中华医学会儿科学分会新生儿学组.中国城市早产儿流行病学初步调查报告[J].中国当代儿科杂志,2005,7(1):25-28.
[3] 周伟勤.极早产儿主要临床问题回顾性分析及人脐带血间充质干细胞制备研究[D].广州:南方医科大学儿科学,2013.
[4] Manuck TA,Rice MM,Bailit JL,et al.Preterm neonatal morbidity and mortality by gestational age:a contemporary cohort[J].Am J Obstet Gynecol,2016,215(1):101-103.
[5] Vohr B.Long-term outcomes of moderately preterm,late preterm,and early term infants[J].Clin Perinatol,2013,40(4):739-751.
[6] 中华儿科杂志编辑委员会,中华医学会儿科学分会儿童保健学组,中华医学会儿科学分会新生儿学组.早产、低出生体重儿出院后喂养建议[J].中华儿科杂志,2016,54(1):6-12.
[7] 刘湘云,陈荣华,赵正言.儿童保健学[M].4版:南京:江苏科学技术出版社,2012.
[8] Goldenberg RL,Culhane JF,Iams JD,et al.Epidemiology and causes of preterm birth[J].Lancet,2008,371(9606):75-84.
[9] 章岚,冷黎,陈英才.早产适于胎龄儿婴儿期追赶生长特点和2至3岁生长偏离的队列研究[J].中国循证儿科杂志,2016,11(5):332-336.
[10] Bocca-Tjeertes I,Bos A,Kerstjens J,et al.Symmetrical and asymmetrical growth restriction in preterm-born children[J].Pediatrics,2014,133(3):e650-e656.
[11] 武华红,李辉.追赶生长研究与进展[J].中国儿童保健杂志,2010,18(2):144-146.
[12] 宋泽宇,李秀红.早产儿早期追赶生长对后期发育影响的研究进展[J].中国儿童保健杂志,2017,25(3):265-267.
[13] Lei X,Chen Y,Ye J,et al.The optimal postnatal growth trajectory for term small for gestational age babies:a prospective cohort study[J].J Pediatr,2015,166(1):54-58.
[14] 田园,张宇鸣,陈菲,等.多学科合作的早产儿系统管理对新生儿重症监护室出院早产儿神经精神发育结局的影响[J].中国儿童保健杂志,2018,26(3):294-297.
[15] 赵凯怡,赵芸,潘静子,等.极低出生体重儿和极早早产儿随访检测及预后影响因素分析[J].中华物理医学与康复杂志,2015,37(1):24-28.