Objectives To understand the epidemic of embryo loss,and to analyze the risk factors for embryo loss,so as to provide scientific suggestions for decreasing the rate of embryo loss. Methods Totally 226 women with embryo loss were enrolled in this study in two counties where furniture manufacturers were located.Meantime,226 normal delivered women were selected as control matched by age,body mass index (BMI) and address (urban or rural areas).The influencing factors of embryo loss in early pregnancy were analyzed. Results The embryo loss rate rose from 4.34% in 2014 to 5.60% in 2016,significantly higher than the birth defect rate at the same period.Multiple regression analysis showed that regular period(OR=0.438,95%CI:0.230-0.830),health care during pregnancy (OR=0.179,95%CI:0.110-0.291) were protective factors for embryo loss.Taking emergency contraception pill during this pregnancy (OR=4.687,95%CI:1.533-14.334),second-hand smoking(OR=1.593,95%CI:1.146-2.215),and purchasing new furniture over the past 6 months(OR=2.572,95%CI:1.302-5.084) were risk factors for embryo loss. Conclusions Embryo development in early pregnancy is influenced by both material and natural environment.Improving life and working environment during pregnancy and accepting health care services in early pregnancy are helpful to reduce embryo loss rate in early pregnancy.
Key words
embryo loss /
prevalence rate /
birth defects
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