Analysis of the related factors for allergic disease secondary to necrotizing enterocolitis

ZOU Shan-ye; LI Qu-bei

doi:10.11852/zgetbjzz2018-0503

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Chinese Journal of Child Health Care ›› 2019, Vol. 27 ›› Issue (1) : 87-90. DOI: 10.11852/zgetbjzz2018-0503

Analysis of the related factors for allergic disease secondary to necrotizing enterocolitis

ZOU Shan-ye, LI Qu-bei

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Abstract

Objective To investigate the correlated factors for allergic disease secondary to necrotizing enterocolitis (NEC) in newborns,in order to provide evidence for clinical diagnosis and treatment. Methods The clinical data of 137 neonates with NEC from 1st January to 31st December,2014 were analyzed and followed-up for three years. The related factors for secondary allergic disease were evaluated by Logistic regression analysis. Results The rate of anaphylactic disease was 36.50% (50/137) after three-year follow-up. Multivariate Logistic regression analysis showed that second-hand smoking(OR=2.833,95%CI:1.066-7.532) and family history of allergy(OR=4.637,95%CI:1.652-13.013) were the independent risk factors of allergic disease in NEC children (P＜0.05),while breastfeeding(OR=0.152,95%CI:0.042-0.547) for at least first 4 months,positive result of fecal occult blood (OR=0.338,95%CI:0.141-0.811) were associated with lower incidence of allergic disease. Conclusions Allergic diseases after NEC are related to many factors. Second-hand smoking and family history of allergy increase the incidence of NEC,so these factors should be avoided. Meantime,breastfeeding is an effective means to reduce the occurrence of allergic diseases that is supposed to be encouraged.

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necrotizing enterocolitis / allergic disease / children

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ZOU Shan-ye, LI Qu-bei. Analysis of the related factors for allergic disease secondary to necrotizing enterocolitis[J]. Chinese Journal of Child Health Care. 2019, 27(1): 87-90 https://doi.org/10.11852/zgetbjzz2018-0503

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