Research progress on the brain development of children with autism spectrum disorders

LIU Jia-ning; CHEN Yan-hui

doi:10.11852/zgetbjzz2018-0484

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Chinese Journal of Child Health Care ›› 2019, Vol. 27 ›› Issue (1) : 51-55. DOI: 10.11852/zgetbjzz2018-0484

Research progress on the brain development of children with autism spectrum disorders

LIU Jia-ning, CHEN Yan-hui

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Abstract

Researches on the structure,neural pathways and neuronal excitability of autism spectrum disorders (ASD) have progressed rapidly in recent years. Studies indicated that abnormalities of brain development in ASD children can be found in early childhood by imaging and elctroencephalogram(EEG) examination,such as abnormalities in the corpus callosum and confusions in the nerve pathways of the white matter.On the other hand,the excitability abnormalities of some neurons is related to the behavioral changes of ASD,and the abnormalities were related to some receptor activities and some signaling pathways. These findings are helpful to explain the pathogenesis mechanism and behavioral manifestation of ASD,and related biological changes could also help to diagnose ASD and provide a breakthrough point for the treatment of ASD.

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autism spectrum disorder / brain development / children / early diagnosis

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LIU Jia-ning, CHEN Yan-hui. Research progress on the brain development of children with autism spectrum disorders[J]. Chinese Journal of Child Health Care. 2019, 27(1): 51-55 https://doi.org/10.11852/zgetbjzz2018-0484

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