Objective To test the levels of myelin basic protein (MBP) and neuron-specific enolase(NSE) in the cerebrospinal fluid (CSF) of children with mycoplasmal pneumonia complicated with encephalitis, in order to explore the clinical value of MBP and NSE in the assessment of mycoplasmal pneumonia complicated with encephalitis. Methods Totally 68 cases with mycoplasmal pneumonia complicated with encephalitis were selected as experimental group (including 36 cases of non-convulsion group,32 cases of convulsion group) and 30 cases of mycoplasmal pneumonia in control group from April 2016 to October 2017.The contents of MBP and NSE in the cerebrospinal fluid (CSF) were tested by enzyme linked immunosorbent assay (ELISA). Result The levels of MBP and NSE in the cerebrospinal fluid of the convulsive group and the non-convulsive group were significantly higher than those in control group (P<0.05), and were also higher in convulsive group than non-convulsive group (P<0.05). Conclusion The content of MBP and NSE in CSF can be used as an index to evaluate the central nervous system injury and injury degree of children with mycoplasmal pneumonia complicated with encephalitis, which is helpful for clinicians to predict the condition and make reasonable diagnosis and treatment as soon as possible.
Key words
mycoplasmal pneumouniae pneumounia /
encephalitis /
myelin basic protein /
neuron-specific enolase
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