Association between the status of vitamin D with overweight and obesity of children in Guangzhou

LUO Hui; LI Hui; CHEN Man-rong; LIU Mei-juan; MEI Shi-wei

doi:10.11852/zgetbjzz2017-25-10-23

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Chinese Journal of Child Health Care ›› 2017, Vol. 25 ›› Issue (10) : 1058-1060. DOI: 10.11852/zgetbjzz2017-25-10-23

Association between the status of vitamin D with overweight and obesity of children in Guangzhou

LUO Hui¹,LI Hui¹,CHEN Man-rong²,LIU Mei-juan¹,MEI Shi-wei¹

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Abstract

Objective To explore the association of the status of vitamin D with overweight and obese children in Guangzhou,and to provide measures for the prevention of vitamin D deficiency. Methods A cross sectional study was used to investigate physical examination and laboratory test among the children in Guangzhou.Chemiluminescence was used to detect the level of serum 25-hydroxy vitamin D [25-(OH)D]. Results The average level of serum 25-(OH)D was (98.57±39.96) nmol/L with (98.58±39.64)nmol/L in boys and (98.56±40.58)nmol/L in girls and there was no statistical difference between different genders(P>0.05).The prevalence rates of vitamin D deficiency and insufficiency were 8.68% and 21.14% respectively,and there was no statistical difference between different genders (P>0.05).With the increasing of age,the level of serum 25-(OH)D decreased (P<0.05),and the prevalence rates of vitamin D deficiency and insufficiency increased (P<0.05).The level of serum 25-(OH)D was lower in overweight and obese children than those in normal children (P<0.05).The prevalence rates of vitamin D deficiency and insufficiency in overweight and obese children were higher than those in normal children (P<0.05).There was negative correlation between 25-(OH)D and BMI (P<0.001). Conclusions The status of vitamin D is poor in school children as well as overweight and obese children in Guangzhou.Comprehensive measures should be taken to improve the status in vitamin D of children especially of school children,overweight and obese children in Guangzhou.

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vitamin D / overweight / obesity / children

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LUO Hui,LI Hui,CHEN Man-rong,LIU Mei-juan,MEI Shi-wei. Association between the status of vitamin D with overweight and obesity of children in Guangzhou[J]. Chinese Journal of Child Health Care. 2017, 25(10): 1058-1060 https://doi.org/10.11852/zgetbjzz2017-25-10-23

References

[1] Camargo CA,Ganmaa D,Frazier AL,et al.Randomized trial of vitamin D supplementation and risk of acute respiratory infection in Mongolia [J].Pediatrics,2012,130(3): 561-567.
[2] Holick MF.Vitamin D status: measurement,interpretation,and clinical application [J].Ann Epidemiol,2009,19(2): 73-78.
[3] 刘运双,薛冰蓉,曾平,等.绵阳市0~14岁人群维生素D水平调查[J].检验医学与临床,2014,11(10):1336-1338.
[4] 章建伟,王卓英.0~9岁儿童维生素D水平的调查[J].浙江预防医学,2015,27(3):229-231.
[5] Vimaleswaran KS,Berry DJ,Lu C,et al.Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts[J].PLos Med,2013,10(2):e1001383.
[6] 祝素萍,杜青,陈妙,等.肥胖儿童免疫状态与维生素D水平相关性研究[J].现代实用医学,2015,27(10):1335-1336.
[7] Holick MF,Binkley NC,Bischoffferrari HA,et al.Evaluation,treatment,and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline[J].J Clin Endocrinol Metab,2011,96(7):1911-1930.
[8] 中国肥胖问题工作组.中国学龄儿童青少年超重、肥胖筛查体重指数值分类标准[J].中华流行病学杂志,2004,25(2):97-102.
[9] Wagner CL,Greer FR.Prevention of rickets and vitamin D deficiency in infants,children and adolescents [J].Pediatrics,2008,122(5): 1142-1152.
[10] 高改兰,李杰,汤淑斌,等.宝鸡地区1874例0～7岁儿童维生素D水平调查研究[J].中国儿童保健杂志,2016,24(1): 33-36.
[11] 周静,尹春福,冯棋琴,等.海南省琼中县中小学生血清维生素D水平分析[J].中国学校卫生,2015,36(9):1304-1305.
[12] Turer CB,Lin H,Flores G.Prevalence of vitamin D deficiency among overweight and obese US children[J].Pediatrics,2013,131(1):152-161.
[13] 蒋新液,裴晶晶,卫雅蓉,等.血清25羟-维生素D3水平与儿童肥胖之间的关系[J].中华实用儿科临床杂志,2014,29(19):1476-1478.
[14] Wood RJ.Vitamin D and Adipogenesis: New Molecularinsights [J].Nutr REV,2008,66(1):40-44.