Objective To explore physical growth of premature infants under corrected age of 6 months and to provide guidance on health care for premature infants. Methods A total of 786 premature infants with complete follow-up data were enrolled.All premature infants were offered early comprehensive intervention and followed up until corrected age of 6 months.Premature infants were divided into different groups according to gestational age (<32、32~33+6、34~35+6、36~36+6 weeks) and the relationship between gestational age and birth weight (small,appropriate and large for gestational age),respectively.Linear mixed model was used to assess changes in physical growth of premature infants. Results Weight,length and head circumference among different gestational age groups (F values were 11.88,29.91 and 19.19,respectively) and different corrected age points (F values was 7678.78,11922.57 and 7913.78,respectively) were significantly different(all P<0.001);Significant difference was also found on weight,length and head circumference among SGA,AGA and LGA infants (F values were 88.01,79.36 and 50.27,respectively,all P<0.001) and different corrected age points (F values were 1 192.38,1 836.58 and 1 225.71,respectively,all P<0.001).At corrected age of 6 months,more than 50% of premature infants were between the 25th and the 75th percentices of Chinese full-term infant reference. Conclusions Physical growth of premature infants is closely related to gestational age and birth weight.Early comprehensive intervention has positive effect on promoting physical growth of premature infants.
Key words
premature infants /
physical growth /
follow-up study /
early intervention
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