Effect of long-term oral use of glucocorticoid on mood and mental state of children with chronic illness

ZHANG Yan; SUN Jing; LIAN Dong-mei; LIU Ao-bo; XIANG Na; LI Yang

doi:10.11852/zgetbjzz2017-25-09-07

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Chinese Journal of Child Health Care ›› 2017, Vol. 25 ›› Issue (9) : 887-886. DOI: 10.11852/zgetbjzz2017-25-09-07

Effect of long-term oral use of glucocorticoid on mood and mental state of children with chronic illness

ZHANG Yan¹,SUN Jing²,LIAN Dong-mei²,LIU Ao-bo¹,XIANG Na¹,LI Yang¹

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Abstract

Objective To analyse the influence of long-term oral use of glucocorticoid on mood and mental state of children with chronic disease.Method Totally 140 children with chronic illness aged from 10 to 18 were selected by convenience sampling to finish the self-designed questionnaire,Piers-Harris Children's Self-concept Scale(PHCSS) and Depression Self-Rating Scale for Children (DSRSC).Multiple hierarchical regression analysis was used to explore the effect of extended oral glucocorticoid on mood and mental state of participants.Results The average score of self-concept scale and depression scale were 55.50±11.49 and 9.11±4.81 respectively.29.0%children reported low level of self-concept(<50 scores)and 15.9% children were with high level of depression.The results of hierarchical regression analysis showed that the long-term oral use of glucocorticoid could explain 5.6% of the variance in self-concept and 3.1% in depression.Conclusion Long-term oral use of glucocorticoid could influence the mood and mental state of children with chronic disease,who are prone to appear low level of self-evaluation and depression disorder.

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long-term / glucocorticoid / self-concept / depression / pediatric patients

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ZHANG Yan,SUN Jing,LIAN Dong-mei,LIU Ao-bo,XIANG Na,LI Yang. Effect of long-term oral use of glucocorticoid on mood and mental state of children with chronic illness[J]. Chinese Journal of Child Health Care. 2017, 25(9): 887-886 https://doi.org/10.11852/zgetbjzz2017-25-09-07

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