Express of PON2 and LTSR in the children of the bronchial asthma and relevance with clinical biological significance

CHENG Wei; WANG Zhen; WANG Jing; YAN Kun

doi:10.11852/zgetbjzz2017-25-08-27

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Chinese Journal of Child Health Care ›› 2017, Vol. 25 ›› Issue (8) : 843-845. DOI: 10.11852/zgetbjzz2017-25-08-27

Express of PON2 and LTSR in the children of the bronchial asthma and relevance with clinical biological significance

CHENG Wei¹,WANG Zhen¹,WANG Jing¹,YAN Kun²

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Abstract

Objective To investigate the relationship between serum paraoxonase 2 and lekukotriene receptor expression in children with bronchial asthma and explore its clinical significance. Methods Compare the serum paraoxonase 2 and leukotriene receptor of different groups in children with bronchial asthma by ELISA,which take the normal children as control. Results There were obvious differences in the expression of the serum paraoxonase 2 and leukotriene receptor between normal children and bronchial asthma cases.Also,there was positive correlation among the severity grade of symptom and their expression level.The r values were 0.81 and 0.73 (P<0.05). Conclusion The paraoxonase 2 and leukotriene receptor can be used as an independent risk factor to detect the prognosis of children with bronchial asthma.

Key words

serum paraoxonase 2 / leukotriene receptors / bronchial asthma / Enzyme-linked immunosorbent assay

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CHENG Wei,WANG Zhen,WANG Jing,YAN Kun. Express of PON2 and LTSR in the children of the bronchial asthma and relevance with clinical biological significance[J]. Chinese Journal of Child Health Care. 2017, 25(8): 843-845 https://doi.org/10.11852/zgetbjzz2017-25-08-27

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