Research progress of neonatal viamin A deficiency

LI Wen-di; WEI Shou-lei; PENG Yun; SHAO Xing-lan; ZHAO Han-qing

doi:10.11852/zgetbjzz2017-25-08-13

PDF(574 KB)

Chinese Journal of Child Health Care ›› 2017, Vol. 25 ›› Issue (8) : 799-802. DOI: 10.11852/zgetbjzz2017-25-08-13

Research progress of neonatal viamin A deficiency

LI Wen-di,WEI Shou-lei,PENG Yun,SHAO Xing-lan,ZHAO Han-qing

Author information +

History +

Abstract

Vitamin A is important lipid soluble vitamin,which is involved in many functions of the body and plays an important role in the development of children's growth.Neonatal vitamin A deficiency is closely related to the occurrence of the disease.Neonatal vitamin A supplementation is currently being considered as policy in countries at risk of deficiency.But at present,many studies challenge this policy.This review focus on current research progress of neonatal vitamin A deficiency,which will better guide clinical diagnosis and treatment.

Key words

vitamin A / neonate / growth and development

Cite this article

EndNote

Ris (Procite)

Bibtex

Download Citations

LI Wen-di,WEI Shou-lei,PENG Yun,SHAO Xing-lan,ZHAO Han-qing. Research progress of neonatal viamin A deficiency[J]. Chinese Journal of Child Health Care. 2017, 25(8): 799-802 https://doi.org/10.11852/zgetbjzz2017-25-08-13

References

[1] World Health Organization (WHO).Global prevalence of vitamin A deficiency in populations at risk 1995-2005[R].Geneva:World Health Organization,2009.
[2] Thorne-Lyman AL,Fawzi WW.Vitamin A and carotenoids during pregnancy and maternal,neonatal and infant health outcomes:a systematic review and meta-analysis[J].Paediatr Perinat Epidemiol,2012,26(1):36-54.
[3] Sommer A,West KP.Vitamin A deficiency:health,vision and survival[M].Oxford,UK:OxfordUnivsersity Press,1996.
[4] Olson JA,Gunning DB,Tilton RA.Liver concentrations of vitamin A and carotenoids,as a function of age and other parameters,of American children who died of various causes[J].Am J Clin Nutr,1984,39(6):903-910.
[5] 顾志勇.维生素A与新生儿疾病关系的临床研究[D].重庆:重庆医科大学,2014.
[6] 刘登礼,何必子.不同胎龄和不同出生体重新生儿出生时血清维生素A水平测定[J].中国新生儿科杂志,2015,30(5):358-360.
[7] Ramakrishnan U,Aburto N,McCabe G,et al.Multimicronutrient interventions but not vitamin A or iron interventions alone improve child growth:results of 3 meta-analyses[J].Nutr,2004,134(10):2592-2602.
[8] Benn CS,Diness BR,Roth A,et al.Effect of 50000 U vitamin A given with BCG vaccine on mortality in infants in Guinea-Bissau:randomised placebo controlled trial[J].BMJ,2008,336(7658):1416-1420.
[9] Biering-Srensen S,Fisker AB,Ravn H,et al.The effect of neonatal vitamin A supplementation on growth in the first year of life among low-birth-weight infants in Guinea-Bissau:two by two factorial randomised controlled trial[J].BMC Pediatr,2013,13:87.
[10] Zhang Y,Wray AE,Ross AC.Perinatal exposure to vitamin A differentially regulates chondrocyte growth and the expression of aggrecan and matrix metalloprotein genes in the femur of neonatal rats[J].Nutr,2012,142(4):649-654.
[11] Wang Z,Dollé P,Cardoso WV,et al.Retinoic acid regulates morphogenesis and patterning of posterior foregut derivatives[J].Dev Biol,2006,297(2):433-445.
[12] Esteban-Pretel G,Marín MP,Renau-Piqueras J,et al.Vitamin A deficiency alters rat lung alveolar basement membrane:reversibility by retinoic acid[J].Nutr Biochem,2010,21(3):227-236.
[13] 程晨.新生儿血清维生素A水平及其与新生儿呼吸窘迫综合征的相关性分析[D].重庆:重庆医科大学,2014.
[14] Meyer S,Gortner L.Early postnatal additional high-dose oral vitamin A supplementation versus placebo for 28 days for preventing bronchopulmonary dysplasia or death in extremely low birth weight infants[J].Neonatology,2014,105(3):182-188.
[15] Moreira A,Caskey M,Fonseca R,et al.Impact of providing vitamin A to the routine pulmonary care of extremely low birth weight infants[J].Matern Fetal Neonatal Med,2012,25(1):84-88.
[16] Uberos J,Miras-Baldo M,Jerez-Calero A,et al.Effectiveness of vitamin a in the prevention of complications of prematurity[J].Pediatr Neonatol,2014,55(5):358-362.
[17] Mallett R,Simmonds S,Kuppurajan A,et al.Neonatal aortic dilatation secondary to vitamin A deficiency[J].Pediatrics,2015,135(5):e1321-1325.
[18] Cabano R,Mannarino S,Bollani L,et al.Neonatal aortic dilatation associated with vitamin A deficiency and its subsequent remission after supplementation therapy[J].Acta Paediatr,2012,101(12):e530.
[19] Diness BR,Christoffersen D,Pedersen UB,et a1.The effect of high-dose vitamin A supplementation given with bacilli Calmette-Gu é rin vaccine at birth on infant rotavirus infection and diarrhea:a randomized prospective study from Guinea-Bissau[J].Infect Dis,2010,202(Suppl):243-251.
[20] 江伟.低剂量维生素A或多种营养素佐治新生儿肺炎[D].重庆:重庆医科大学,2008.
[21] McDonald SL,Savy M,Fulford AJ,et al.A double blind randomized controlled trial in neonates to determine the effect of vitamin A supplementation on immune responses:The Gambia protocol[J].BMC Pediatr,2014,14:92.
[22] Aage S,Kiraly N,Da Costa K,et al.Neonatal vitamin A supplementation associated with increased atopy in girls[J].Allergy,2015,70(8):985-994.
[23] Kiraly N,Benn CS,Biering-Srensen S,et al.Vitamin A supplementation and BCG vaccination at birth may affect atopy in childhood:long-term follow-up of a randomized controlled trial[J].Allergy,2013,68(9):1168-1176.
[24] Mazumder S,Taneja S,Bhatia K,et a1.Efficacy of early neonatal supplementation with vitamin A to reduce mortality in infancy in Haryana,India (Neovita):a randomised,double-blind,placebo-controlled trial[J].Lancet,2015,385(9975):1333-1342.
[25] Masanja H,Smith ER,Muhihi A,et a1.Effect of neonatal vitamin A supplementation on mortality in infants in Tanzania (Neovita):a randomised,double-blind,placebo-controlled trial[J].Lancet,2015,385(9975):1324-1332.
[26] Edmond KM,Newton S,Shannon C,et al.Effect of early neonatal vitamin A supplementation on mortality during infancy in Ghana (Neovita):a randomised,double-blind,placebo-controlled trial[J].Lancet,2015,385(9975):1315-1323.
[27] Benn CS,Diness BR,Balde I,et al.Two different doses of supplemental vitamin A did not affect mortality of normal-birth-weight neonates in Guinea-Bissau in a randomized controlled trial[J].Nutr,2014,144(9):1474-1479.
[28] WHO.Guideline:Neonatal vitamin A supplementation[Z].Geneva,World Health Organization,2011.
[29] Humphrey JH,Ichord RN.Safety of vitamin A supplementation of postpartum women and young children[J].Food and Nutrition Bulletin,2011,22:311-319.