Objective To observe the clinical effect of Jiao's scalp acupuncture combined with Zhi nine in early treatment of children with mental retardation. Method The children were randomly divided into two groups,treatment group including 50 cases and control group including 64 cases,treatment group was treated by scalp acupuncture combined with focal type Zhi nine plus rehabilitation treatment,control group with rehabilitation treatment alone,Gesell scale was used to evaluate the DQ value and total DQ value before and after treatment in 5 areas. Results The DQ and the total DQ values in the five functional areas of the treatment group were significantly higher than control group before treatment (P<0.05), the total DQ value and the DQ value of gross motor,verbal ability,social intercourse functional areas after treatment in the treatment group were significantly higher than control group (P<0.05),but the DQ value of the fine motor and the adaptability region had no significant difference in treatment group. Conclusion Early treatment by Jiao's scalp acupuncture accompanied with Zhi nine has good clinical curative effect on children with mental retardation.