Objective To collect information on nutrition of vitamin D in Xuzhou children aged 0~5 in winter,and to instruct parents how to properly use vitamin D. Method The serum samples were collected from 242 cases at the age of 0~5 who received conventional healthcare in the outpatient of children healthcare at the Xuzhou Maternial and Child Health Care Hospital,and the serum levels of 25-hydroxy vitaminD [25(OH)D]were determined using immunochromatography. Results The mean level of 25(OH)D was (51.34±19.38) nmol/L in these 242 cases aged 0~5.108 cases,accounting for 44.63% of them,exhibited adequate levels of 25(OH)D,while 55.37% of them showed low levels of 25(OH)D (deficient in 26.45%,scarce in 28.93%).There was no significant difference in the level of 25(OH)D between girls and boys at the age of 0~5 (P>0.05).Children at the age of 3~5 had significantly lower level of 25(OH)D compared to those less than 1 year old (P<0.05). Conclusions In Xuzhou City,children at the age of 0~5 years old generally exhibited low levels of 25(OH)D.Therefore,attention should be paid to the 25(OH)D test and supplementation.
Key words
25-hydroxyvitamin D /
serum concentration /
immunochromatography /
children /
winter
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References
[1] Holick MF.Vitamin D deficiency[J].N Engl J Med,2007,357(3):266-281.
[2] Holick MF,Binkley NC,Bischoff-Ferrari HA,et al.Evaluation,treatment,and prevention of vitamin D deficiency:an Endocrine Society clinical practice guideline[J].J Clin Endocrinol Metab,2011,96(7):1911-1930.
[3] Hohck MF.Vitamin D Deficiency[J].N Engl J Med,2007,357:266-281.
[4] 《中华儿科杂志》编辑委员会,中华医学会儿科学分会儿童保健学组,全国佝偻病防治科研协作组.维生素D 缺乏性佝偻病防治建议[J].中华儿科杂志,2008,46(2):190-191.
[5] Holick MF.Vitamin D,sunlight and cancer connection[J].Anticancer Agents Med Chem,2013,13(1):70-82.
[6] Alvarez-Rodriguez L,Lopez-Hoyos M,Garcia-Unzueta M,et al.Age and low levels of circulating vitamin D are associated with impaired innate immune function [J].J Leukoc Biol,2012,91(5):829-838.
[7] Camargo CA,Ganmaa D,Frazier AL,et al.Randomized trial of vitamin D supplementation and risk of acute respiratory infection in Mongolia [J].Pediatrics,2012,130(3):e561-e567.
[8] 肖玉联,都萍,谭美珍,等.单纯性肥胖儿童血清维生素D 水平检测及干预效果观察[J].广东医学院学报,2012,30(6):270-271.
[9] 叶莉莉,高玲娟,顾平清,等.南京市0～6岁婴幼儿25-羟维生素D检测分析[J].国际检验医学杂志,2012,16(1):16-17.
[10] 嵇建峰,王峰,陈志华.975名婴幼儿25-(OH)D水平分析[J].中国生育健康杂志,2010,21(5):285-286.
[11] 王丹华.早产/低出生体重儿喂养建议[J].中华儿科杂志,2009,47(4):508-510.
[12] 吴康敏.儿童维生素D、钙营养合理补充[J].中国实用儿科杂志,2012,27(3):16-169.
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