Objective To analyze the relationship between cesarean section and incidence of cerebral palsy. Methods Using the keywords (cerebral palsy,causes or risk factors or caesarean section),a search was performed to collect the case-control studies on the risk factors of cerebral palsy childhren from 1990 to 2016,the data base included the China journal full text database (CNKI),Wanfang database,Chinese VIP database (VIP) and PubMed,MEDLIN,OVID,the Cochrane library database.The included literatures were conducted the Meta analysis by the Manager 5.2 Review software,the test level of α=0.05. Results A total of 9 literatures were included,2 Chinese,7 English.And the observation group were included 3 327 children with cerebral palsy children,totally 852 were performed by caesarean section; and the control group were included 1 700 535 children,a total of 126 323 performed by caesarean section.The analysis Results were as follows:the relationship between the cesarean section and cerebral palsy children(OR=1.61;95%CI:0.93~2.79;I2=95%);Term cesarean section and cerebral palsy children (OR=2.04,95%CI:1.81~2.29;I2=23%); premature caesarean section and cerebral palsy children (OR=0.84;95%CI:0.63~1.13;I2=94%); emergency caesarean and cerebral palsy children (OR=9.77;95%CI:7.37~12.96;I2=95%). Conclusion Cesarean section is not a protective factor for cerebral palsy,but about the emergency caesarean section,we need to conduct a further study to demonstrate the relationship with cerebral palsy.
Key words
cesarean /
cerebral palsy /
Meta analysis
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