Objective To provide the theory for the prevention and treatment of premature cerebral palsy,and analyze the relationship between the risk factors and premature cerebral palsy. Methods From Oct.2008 to Oct.2014,70 cases of cerebral palsy from the disabled rehabilitation were selected as research object,140 cases of healthy examined children were selected as control group with the corresponding period.The clinical data of all the subjects were analyzed. Results A total of 70 cases of cerebral palsy were all accompanied by different degree of movement disorders.For single factor analysis,the history of bad production,repeated vaginal bleeding during pregnancy,elderly parturient,abnormal amniotic fluid,pregnant infection,cord around neck,malposition,whose fathers drank,weight ≤1.5 kg,dystocia,fetal intrauterine distress,neonatal asphyxia,pathologic jaundice,hypoxic ischemic encephalopathy,pneumonia of newborn were all related with cerebral palsy.For Logistic analysis,the history of bad production,abnormal amniotic fluid,fetal intrauterine distress,neonatal asphyxia,pathologic jaundice,hypoxic ischemic encephalopathy,pneumonia of newborn were all risk factors for cerebral palsy. Conclusions Cerebral palsy is related with a variety of factors during antepartum and intrapartum and postpartum periods.Positive prevention,pregnancy examination and perinatal care according to the risk factors for cerebral palsy would reduce the incidence of cerebral palsy.